Neurology Practice Test 5
Neurology NCLEX Practice Test
Neurology is a key topic within the NCLEX test plan, located under Nursing Science → Clinical Foundations → Neurology. This section integrates neuroanatomy and function into neurologic assessments and early detection of deficits. Each test contains 50 questions designed to mirror the difficulty and variety of the real exam.
This is the 5th part of the Neurology series. To explore all practice tests under this topic, use the “Back to Main Topic” button at the end of the page.
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In the Neurology Study Cards section, shared by real NCLEX candidates, you’ll find concise summaries and high-yield insights related to the most tested concepts. It’s a perfect space to reinforce challenging topics and sharpen your recall through quick, focused repetitions. Short, powerful, and repeatable!
Neurology Practice Test 5
From which part of the brain does the spinal cord originate?
- Pons
- Cerebellum
- Medulla Oblongata
Explanation: Answer reason: The spinal cord is a continuation of the brainstem beginning at the foramen magnum where the medulla oblongata transitions into the spinal cord.
Which condition occurs due to a lack of blood supply to a part of the brain?
- Epilepsy
- Meningitis
- Stroke
- Parkinson’s disease
Explanation: Answer reason: A stroke results from interrupted cerebral blood flow causing ischemia and infarction. Epilepsy is a seizure disorder, meningitis is infection of the meninges, and Parkinson’s disease is a neurodegenerative movement disorder.
A nurse touches the patient's face with a cotton swab on the forehead, cheek, and chin and instructs the patient to clench the teeth. The nurse is assessing?
- Motor function of trigeminal nerves
- Sensory function of trigeminal nerves
- Both motor and sensory function of trigeminal nerves
- Motor function of facial nerves
Explanation: Answer reason: Light touch to the forehead, cheek, and chin tests CN V sensory branches (V1–V3), while clenching the teeth tests CN V motor function to muscles of mastication; together they assess both motor and sensory functions of the trigeminal nerve.
A condition, causing the affected person to be unable to understand or comprehend the language (poor comprehension with intact repetition (fluent output) is termed as?
- Conduction aphasia
- Broca's aphasia
- Global aphasia
- Wernicke's aphasia
Explanation: Answer reason: Wernicke's aphasia presents with fluent speech and impaired language comprehension. Broca's is nonfluent, conduction has impaired repetition with relatively preserved comprehension, and global affects all modalities.
Assess visual activity with Snellen chart and perform ophthalmoscopic exam, check peripheral vision by confrontation, check color vision?
- Cranial Nerve II testing
- Cranial nerve V testing
- Cranial nerve VII testing
- None of the above
Explanation: Answer reason: Visual acuity, visual fields by confrontation, color vision, and fundoscopic exam assess the optic nerve (CN II).
What is the name of the biggest part of the human brain?
- Cerebrum
- Cerebellum
- Brainstem
- None of these
Explanation: Answer reason: The cerebrum is the largest part of the human brain, comprising the two cerebral hemispheres. The cerebellum and brainstem are smaller structures.
Which of the following is not a neurotransmitter?
- Cortisone
- Acetylcholine
- Epinephrine
- Norepinephrine
Explanation: Answer reason: Cortisone is a glucocorticoid hormone from the adrenal cortex, not a neurotransmitter. Acetylcholine, epinephrine, and norepinephrine act as neurotransmitters.
What covers the spinal cord?
- Meninges
- Ganglia
- Tissue
- Peritoneum lobe
Explanation: Answer reason: The spinal cord is enclosed by the three meninges (dura mater, arachnoid mater, pia mater). Ganglia are clusters of neuronal cell bodies, and the peritoneum is an abdominal membrane.
Positive Brudzinski and Kernig’s signs are manifestations of which condition?
- Meningitis
- Encephalitis
- Pneumonia
- Glomerulonephritis
Explanation: Answer reason: Brudzinski and Kernig signs indicate meningeal irritation, a classic finding in meningitis.
The corpus callosum of the cerebrum is made up of which type of matter?
- White matter
- Yellow matter
- Grey matter
- Pink matter
Explanation: Answer reason: The corpus callosum consists of myelinated commissural axons, which constitute white matter.
What is the term for the inability to carry out normal activities despite intact motor function?
- Anhedonia
- Apraxia
- Apathy
- Amnesia
Explanation: Answer reason: Apraxia is the inability to perform purposeful activities despite intact motor strength and coordination; other options refer to loss of pleasure, lack of interest, or memory loss.
How many pairs of spinal nerves are there?
- 28 pairs
- 30 pairs
- 31 pairs
- 33 pairs
Explanation: Answer reason: Humans have 31 pairs of spinal nerves: 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal.
What is the term for the inability to speak or understand spoken words?
- Agnosia
- Apraxia
- Aphasia
- Insomnia
Explanation: Answer reason: Aphasia is a language disorder causing impaired speaking or comprehension. Agnosia is failure to recognize objects, apraxia is impaired motor planning, and insomnia is a sleep problem.
What is the most common cause of tonic-clonic seizures in a 23-year-old client?
- Stroke
- Electrolyte imbalance
- Head trauma
- Congenital brain defect
Explanation: Answer reason: In young adults, new-onset generalized (tonic–clonic) seizures most commonly result from head injury. Stroke is more common in the elderly; congenital defects present earlier; electrolyte imbalance is a less common cause in this age group.
Which of the following functions is influenced by the autonomic nervous system?
- Knee-jerk response
- Pupillary reflex
- Peristalsis of the intestine
- Blinking of eye
Explanation: Answer reason: Autonomic nervous system controls involuntary smooth muscle activity; gastrointestinal motility (peristalsis) is a classic ANS-regulated function via the enteric system modulated by parasympathetic and sympathetic inputs. Knee-jerk and blinking are somatic reflex/voluntary actions.
Which cranial nerve regulates heart rate?
- VII (Facial)
- IX (Glossopharyngeal)
- X (Vagus)
- VIII (Vestibulocochlear)
Explanation: Answer reason: The vagus nerve (CN X) provides parasympathetic innervation to the heart, acting on the SA and AV nodes to slow heart rate.
Which of the following is not a memory disorder?
- Amnesia
- Hypermnesia
- Paramnesia
- Anaemia
Explanation: Answer reason: Amnesia, hypermnesia, and paramnesia are types of memory disorders; anemia is a hematologic condition and not a disorder of memory.
Neuron is the study of what?
- Kidney
- Liver
- Lungs
- Nerve
Explanation: Answer reason: The prefix neuro- refers to nerves; neurons are nerve cells. Thus the correct focus of study is nerves.
Which of the following is not a motor cranial nerve?
- Oculomotor nerve
- Trochlear nerve
- Accessory nerve
- Optic nerve
Explanation: Answer reason: The optic nerve (CN II) is purely sensory for vision, not motor. The oculomotor (III), trochlear (IV), and accessory (XI) are motor cranial nerves.
The nurse is caring for the client following a cerebral vascular accident. Which portion of the brain is responsible for taste, smell, and hearing?
- Occipital
- Frontal
- Temporal
- Parietal
Explanation: Answer reason: The temporal lobe contains the primary auditory cortex and olfactory areas and is commonly associated with taste, smell, and hearing. Occipital is vision; frontal is motor/executive functions; parietal is somatosensory.
The client is admitted to the unit after a motor vehicle accident with a temperature of 102°F rectally. The most likely explanations for the elevated temperature is that?
- There was damage to the hypothalamus.
- He has an infection from the abrasions to the head and face.
- He will require a cooling blanket to decrease the temperature.
- There was damage to the frontal lobe of the brain.
Explanation: Answer reason: The hypothalamus regulates body temperature; head trauma can cause hypothalamic injury leading to hyperthermia. Infection from abrasions is unlikely immediately post-accident, option C is an intervention not an explanation, and the frontal lobe is not a temperature-control center.
A young child is admitted for treatment of lead poisoning. The nurse recognizes that the MOST serious effect of chronic lead poisoning is?
- Central nervous system damage
- Moderate anemia
- Renal tubule damage
- Growth impairment
Explanation: Answer reason: Lead is a potent neurotoxin; chronic exposure most severely damages the CNS, causing cognitive deficits, encephalopathy, seizures, and even death—more serious than anemia, renal tubular effects, or growth delays.
In addition to disturbances in mental awareness and orientation, a client with cognitive impairment is also likely to show loss of ability in?
- Hearing speech and sight
- Endurance, strength and mobility
- Learning, creativity and judgment
- Balance, flexibility and coordination
Explanation: Answer reason: Cognitive impairment primarily affects higher-order cognitive functions such as learning, executive function, creativity, and judgment rather than sensory input, pure motor endurance, or balance alone.
Which of the following cranial nerves are present in the posterior fossa?
- 3rd to 12th
- 4th to 12th
- 5th to 12th
- 6th to 12th
Explanation: Answer reason: The posterior cranial fossa contains the pons, medulla, and cerebellum; cranial nerves V–XII arise from or course through this region. CN III and IV are associated with the midbrain above the tentorium, not the posterior fossa.
Clear fluid draining from the ear and nose is indicative of which condition?
- Rhinorrhea
- Basilar skull fracture
- Otitis media
- Cerebral edema
Explanation: Answer reason: CSF leak (clear drainage from ear or nose: otorrhea/rhinorrhea) commonly follows a basilar skull fracture due to dural tear.
After a brain attack, a client is unable to differentiate between heat, cold, sharp, and dull sensory stimulation; which lobe of the brain is likely affected?
- Frontal
- Parietal
- Occipital
- Temporal
Explanation: Answer reason: The parietal lobe contains the primary somatosensory cortex responsible for processing temperature and pain; damage impairs discrimination of heat/cold and sharp/dull.
Which shunt is most commonly used in the management of hydrocephalus?
- Ventriculopleural shunt
- Ventriculoperitoneal shunt
- Ventriculoatrial shunt
- Ventriculoureteric shunt
Explanation: Answer reason: A ventriculoperitoneal (VP) shunt is the standard and most commonly used diversion for CSF in hydrocephalus due to ease of placement and lower complication rates compared with ventriculoatrial or pleural shunts.
Foot drop occurs due to injury of which nerve?
- Sciatic nerve
- Superficial peroneal artery
- Peroneal nerve
- Brachial plexus
Explanation: Answer reason: Foot drop is classically due to injury of the common peroneal nerve, which denervates dorsiflexors via the deep peroneal branch.
What type of receptors are affected by tactile, painful, and thermal stimuli?
- Protective regulation
- Temperature regulation
- Sense organ
- Acrosome
Explanation: Answer reason: Touch, pain, and temperature are somatic sensations detected by sensory receptors in the skin (cutaneous sense organs). The other options are not receptor types.
What is another name for the cerebrum?
- Hypothalamus
- Thalamus
- Cerebellum
- Midbrain
Explanation: Answer reason: Correct synonym for cerebrum is telencephalon. Thalamus and hypothalamus are diencephalon structures, cerebellum is hindbrain, and midbrain is mesencephalon.
At what age does the glabella reflex disappear?
- 4 months
- 1 year
- 5 years
- 7 years
- Never disappears
Explanation: Answer reason: The glabellar reflex is a primitive frontal release reflex present in infancy that is normally inhibited as frontal pathways mature; it typically disappears by about 1 year. Persistence (non-habituation) later in life is abnormal, e.g., Myerson sign.
Which cranial nerve is mostly affected in bulbar palsy?
- 9th Cranial Nerve
- 10th Cranial Nerve
- 11th Cranial Nerve
- 12th Cranial Nerve
Explanation: Answer reason: Bulbar palsy is a lower motor neuron lesion of the medulla primarily involving CN IX–XII; the vagus nerve (CN X) is most commonly affected due to its major role in palatal and pharyngeal muscles causing dysphagia and dysphonia.
Which neurological disorder is characterized by progressive muscle weakness and exacerbations?
- ALS
- MS
- Parkinson's
- Huntington's
Explanation: Answer reason: Multiple sclerosis has a relapsing-remitting course with exacerbations and can cause progressive weakness, unlike ALS, Parkinson's, or Huntington's which do not have exacerbations.
Which of the following are cranial nerves except?
- Trigeminal nerve
- Olfactory nerve
- Sciatic nerve
- Glossopharyngeal nerve
Explanation: Answer reason: Trigeminal (V), olfactory (I), and glossopharyngeal (IX) are cranial nerves; the sciatic nerve is a peripheral nerve from the lumbosacral plexus, not a cranial nerve.
What type of seizure is characterized by uncontrollable jerking movements?
- Tonic seizure
- Absence seizure
- Myoclonic seizure
- Clonic seizure
Explanation: Answer reason: Clonic seizures feature rhythmic, repetitive jerking of muscles. Tonic causes stiffening, absence causes brief staring, and myoclonic are brief shock-like jerks rather than sustained jerking.
Which part of the brain is known as the seat of intelligence?
- Hypothalamus
- Thalamus
- Cerebellum
- Cerebrum
Explanation: Answer reason: Higher cognitive functions such as reasoning, memory, and intelligence are primarily mediated by the cerebral cortex of the cerebrum.
Meningitis is inflammation of which part of the body?
- Brain
- Spinal cord
- Brain stem
- Meninges
Explanation: Answer reason: Meningitis is inflammation of the meninges, the protective membranes covering the brain and spinal cord.
Where are Betz cells found?
- Axon
- Cortical motor area of brain
- Pyramidal cells
- Primary motor cortex
- All
Explanation: Answer reason: Betz cells are giant pyramidal neurons located in layer V of the primary motor cortex (precentral gyrus).
What is the term for one-sided head pain?
- Trauma
- Tumor
- Seizure
- Migraine
Explanation: Answer reason: Migraine headaches classically present with unilateral head pain; the other options are not terms for one-sided head pain.
A patient came to physiotherapy OPD with a baseball blow to the posterior neck, creating sudden pressure in the posterior triangle. On assessment, the patient is unable to rotate the scapula during abduction. Which nerve is damaged and which muscle does it supply?
- Thoracodorsal nerve, latismmusdorsi
- Axillary nerve, Deltoid
- Long thoracic nerve, serratus anterior
- Dorsal scapular nerve, Rhomboid major
Explanation: Answer reason: Upward rotation of the scapula, necessary for full abduction, is produced primarily by the serratus anterior (innervated by the long thoracic nerve) and trapezius. Injury to the long thoracic nerve in the posterior triangle impairs this rotation, causing difficulty with abduction and scapular winging.
A patient presented to physiotherapy OPD with pain along the medial side of the arm, forearm and little and ring finger. After assessment you came to know that this nerve originates from medial cord of brachial plexus. Which nerve is involved?
- Medial pectoral nerve
- Medial cutaneous nerve of arm and forearm
- Ulnar nerve
- Medial root of median nerve
Explanation: Answer reason: Pain involving the little and ring fingers is characteristic of ulnar nerve involvement. The ulnar nerve is a terminal branch of the medial cord of the brachial plexus. Medial cutaneous nerves supply skin of arm/forearm only and do not account for finger symptoms.
Which of the following fibers participates in high-frequency pain transmission?
- Type A delta and C fibers
- Type A alpha fibers
- Type B fibers
- Type A beta fibers
Explanation: Answer reason: Pain (nociception) is carried by A-delta fibers for fast, sharp pain and C fibers for slow, dull pain. A-alpha, A-beta, and B fibers are not primary pain fibers.
A client is admitted for treatment of a frontal lobe brain tumor. Which of the following assessments would the nurse expect to find?
- Respiratory depression
- Emotional lability
- Hormonal imbalance
- Visual field deficits
Explanation: Answer reason: Frontal lobe lesions affect affect, judgment, and behavior, commonly causing emotional lability. Respiratory depression is brainstem, hormonal imbalance is hypothalamic/pituitary, and visual field deficits are typically occipital or optic pathway.
Select the brain and spinal cord regions, which are involved in the transmission of pain?
- The limbic system, including the amygdaloidal nucleus and the hypothalamus
- The ventral and medial parts of the thalamus
- The substantia gelatinosa
- All of the above
Explanation: Answer reason: All listed structures participate in nociception: substantia gelatinosa (dorsal horn processing), thalamic nuclei (relay and perception), and limbic/hypothalamic areas (affective-autonomic components).
Which of the following supraspinal structures is implicated in pain-modulating descending pathways?
- The midbrain periaqueductal gray
- The hypothalamus
- The aria postrema
- The limbic cortex
Explanation: Answer reason: The periaqueductal gray (PAG) in the midbrain is the key supraspinal center that initiates descending pain inhibition via projections to the rostral ventromedial medulla and spinal cord, utilizing endogenous opioids.
Jane had an injury to her cerebellum. Which of the following is likely to occur?
- Inability to see clearly
- Difficulty of hearing music
- Difficulty on swallowing fluids
- Difficulty of balancing herself
Explanation: Answer reason: The cerebellum coordinates balance and coordination; damage commonly causes ataxia and difficulty maintaining balance. Vision, hearing, and swallowing are primarily mediated by other brain regions.
Which neurotransmitter is the cause of convulsions in eclampsia?
- Glutamate
- Serotonin
- Noradrenaline
- Acetylcholine
Explanation: Answer reason: Seizures result from excessive excitatory neurotransmission via glutamate (e.g., NMDA receptors). Magnesium sulfate treats eclampsia partly by antagonizing NMDA receptors, supporting glutamate’s role.
Which nerve is called the musician's nerve?
- Radial nerve
- Ulnar nerve
- Axillary nerve
- Median nerve
Explanation: Answer reason: The ulnar nerve is known as the musician's nerve because it innervates many intrinsic hand muscles responsible for fine finger movements used in playing instruments.
What is the EEG pattern in REM sleep?
- High amplitude, slow waves
- Low amplitude, rapid waves
- High amplitude, rapid waves
- Low amplitude, slow waves
Explanation: Answer reason: REM sleep shows low-voltage, high-frequency EEG activity (sawtooth/beta-like), hence low amplitude and rapid waves.
Where is the respiratory center of the body located?
- Cerebellum
- Medulla Oblongata
- Cerebrum
- Pons
Explanation: Answer reason: Primary respiratory centers (dorsal and ventral respiratory groups) reside in the medulla oblongata, which generates the basic rhythm of breathing. The pons modulates but is not the main center.
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