Neurology Practice Test 3
Neurology NCLEX Practice Test
Neurology is a key topic within the NCLEX test plan, located under Nursing Science → Clinical Foundations → Neurology. This section integrates neuroanatomy and function into neurologic assessments and early detection of deficits. Each test contains 50 questions designed to mirror the difficulty and variety of the real exam.
This is the 3rd part of the Neurology series. To explore all practice tests under this topic, use the “Back to Main Topic” button at the end of the page.
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In the Neurology Study Cards section, shared by real NCLEX candidates, you’ll find concise summaries and high-yield insights related to the most tested concepts. It’s a perfect space to reinforce challenging topics and sharpen your recall through quick, focused repetitions. Short, powerful, and repeatable!
Neurology Practice Test 3
Wrist drope is most commonly caused by injury to which nerve?
- Radial nerve
- Musclocutaneous nerve
- Ulnar nerve
- Median nerve
Explanation: Answer reason: Wrist drop results from loss of wrist and finger extension due to radial nerve palsy, which innervates the extensor muscles of the forearm.
Which device is used to detect brain wave activity?
- ECG
- EEG
- MRI
- Endoscope
Explanation: Answer reason: EEG (electroencephalogram) records electrical activity of the brain. ECG is for heart rhythms, MRI provides imaging, and an endoscope visualizes internal cavities.
Which cranial nerve is responsible for facial expressions?
- Optic nerve
- Trigeminal nerve
- Facial nerve
- Vagus nerve
Explanation: Answer reason: The facial nerve (cranial nerve VII) innervates the muscles of facial expression. Optic (II) is vision, trigeminal (V) provides facial sensation and mastication, and vagus (X) controls parasympathetic and laryngeal/pharyngeal functions.
What is the most common cause of dementia in adults?
- Alzheimer's
- Multiinfarct
- Pick's disease
- Metabolic cause
Explanation: Answer reason: Alzheimer's disease is the leading and most common cause of dementia in adults; vascular (multi-infarct) dementia is a common second cause, while Pick's disease and metabolic causes are less frequent.
Which type of seizure is characterized by a sudden loss of muscle tone lasting a few seconds in a client with epilepsy?
- Atonic seizure
- Tonic-clonic seizure
- Absence seizure
- Complex partial seizure
Explanation: Answer reason: Atonic (drop) seizures cause sudden brief loss of postural muscle tone. Tonic-clonic involves stiffening and jerking, absence causes brief staring, and complex partial involves impaired awareness without sudden loss of tone.
What is the primary cause of tonic-clonic seizures in adults older than 20 years who have never had a seizure before?
- Head trauma
- Electrolyte imbalance
- Congenital defect
- Epilepsy
Explanation: Answer reason: In adults with new-onset generalized seizures, structural causes—especially head trauma—are the most common. Electrolyte imbalance can cause seizures but is less common; congenital defects present earlier; epilepsy is a diagnosis, not an initial cause.
Which clinical features are commonly associated with epilepsy?
- Loss of consciousness, seizures, confusion, stiffness
- Fever, rash, headache, nausea
- Chest pain, shortness of breath, dizziness
- Abdominal pain, diarrhea, vomiting
Explanation: Answer reason: Epilepsy is a neurologic disorder characterized by recurrent seizures; typical manifestations include loss of consciousness, tonic stiffness, and postictal confusion.
Which of the following scenarios is most likely to result in a brachial plexus injury?
- A client experiencing stroke
- A newborn with difficult delivery
- A client with multiple sclerosis
- An elderly person with osteoporosis
Explanation: Answer reason: Traction on the infant’s shoulder/neck during a difficult delivery (e.g., shoulder dystocia) commonly injures the brachial plexus, especially C5–C6 (Erb palsy). The other scenarios are not typical causes.
Which of the following statements regarding injury to the common peroneal nerve is false?
- It causes foot drop
- Anaesthesia of sole of foot
- Loss of dorsiflexion of toes
- Results from injury to neck of fibula
Explanation: Answer reason: Common peroneal nerve injury causes foot drop with loss of dorsiflexion and often occurs at the neck of the fibula. Sensation of the sole is supplied by the tibial nerve, not the common peroneal; therefore anesthesia of the sole is false.
Which of the following is a cause of increased intracranial pressure (ICP)?
- Bleeding (stroke)
- Inflammation of brain tissue (meningitis, trauma)
- Increased cerebrospinal fluid (CSF)
- Brain tumors
Explanation: Answer reason: Intracranial hemorrhage acutely increases intracranial volume, rapidly raising ICP. (Other listed conditions can also raise ICP, but bleeding is a classic direct cause.)
What characterizes a positive Babinski sign?
- Dorsiflexion of the big toe and fanning of the other toes
- Plantar flexion of all toes
- No response at all
- Involuntary knee jerk
Explanation: Answer reason: A positive Babinski sign is extension (dorsiflexion) of the great toe with fanning of the other toes, indicating an upper motor neuron lesion in adults. Plantar flexion is the normal response.
What is the type of amnesia in which a patient is unable to recall past events?
- Retrograde amnesia
- Anterograde amnesia
- Circumscribed amnesia
- Paramnesia
Explanation: Answer reason: Retrograde amnesia is loss of memory for events that occurred before the onset of the condition; anterograde is inability to form new memories, circumscribed is localized to a period, and paramnesia is memory distortion.
A patient with a history of cocaine abuse reports feeling that something is moving on their body; which type of hallucination is this an example of?
- Kinesthetic hallucination
- Haptic hallucination
- Macropsia
- Lilliput hallucination
Explanation: Answer reason: Tactile (haptic) hallucinations involve sensations on the skin, such as insects crawling or movement, commonly seen with cocaine use. Kinesthetic involves internal body movement; macropsia and Lilliputian are visual disturbances.
A lady with diplopia suddenly falls down and cannot reach the phone due to damage to which artery?
- Anterior cerebral artery
- Anterior choroidal artery
- Middle cerebral artery
- Posterior cerebral artery
- Middle meningeal artery
Explanation: Answer reason: An MCA stroke typically causes contralateral face and upper-extremity weakness and gaze deviation, making the patient unable to reach with the arm. ACA affects the leg, PCA causes visual field loss, anterior choroidal/internal capsule pattern is less specific here, and middle meningeal artery relates to epidural hemorrhage.
Which symptom does the nurse recognize as bradykinesia in a client with Parkinson's disease?
- Intentional tremor
- Paralysis of limbs
- Muscle spasm
- Lack of spontaneous movement
Explanation: Answer reason: Bradykinesia is slowness and poverty of movement, manifested as decreased or absent spontaneous movement; tremor, paralysis, and spasm are not definitions of bradykinesia.
Which assessment finding supports a diagnosis of a stroke impacting the occipital lobe?
- Homonymous hemianopia
- Impaired proprioception
- Expressive aphasia
- Impulsivity
Explanation: Answer reason: The occipital lobe is the primary visual cortex; lesions from stroke commonly cause visual field defects such as homonymous hemianopia. The other findings relate to parietal (proprioception) or frontal/Broca's area (expressive aphasia, impulsivity).
What is the primary function of the sixth cranial (abducens) nerve?
- Movement of the eyeball
- Taste perception
- Closure of epiglottis
- Movement of the tongue
Explanation: Answer reason: Cranial nerve VI (abducens) innervates the lateral rectus muscle to abduct the eye, controlling eyeball movement. Taste involves CN VII/IX, epiglottis closure is via vagus, and tongue movement is CN XII.
Which sentence is incorrect regarding neurons?
- One neuron has one axon and many dendrites
- They can divide
- Neurons are supported by neuroglia
- For survival, neurons need continuous supply of oxygen and glucose
Explanation: Answer reason: Mature neurons are generally amitotic and do not divide; the other statements are true of neurons.
Which cranial nerve is the smallest in humans due to having the least number of axons?
- Optic nerve
- Trochlear nerve
- Abducens nerve
- Hypoglossal nerve
Explanation: Answer reason: The trochlear nerve (CN IV) contains the fewest axons of all cranial nerves, making it the smallest.
If IQ level is less than 20, then what type of mental retardation is indicated?
- Mild mental retardation
- Moderate mental retardation
- Profound mental retardation
Explanation: Answer reason: An IQ below about 20–25 corresponds to profound intellectual disability.
Which spinal nerve is the only one without a corresponding dermatome?
- C1
- C2
- T1
- L1
Explanation: Answer reason: C1 (suboccipital nerve) has no cutaneous sensory distribution and therefore no dermatome.
Which of the following organs cannot be transplanted?
- Kidney
- Heart
- Lung
- Brain
Explanation: Answer reason: Kidney, heart, and lungs are routinely transplanted; the brain cannot be transplanted due to the impossibility of reconnecting its complex neural networks and identity-defining integration.
The cells that create a myelin sheath around peripheral nerve axons are called?
- Schwann cells
- Satellite cells
- Oligodendrocytes
- Osteocytes
Explanation: Answer reason: Schwann cells form the myelin sheath in the peripheral nervous system; oligodendrocytes do so in the CNS.
Which of the following nerves has only motor functions?
- Olfactory
- Facial
- Glossopharyngeal
- Hypoglossal
Explanation: Answer reason: The hypoglossal nerve (CN XII) is purely motor, innervating tongue muscles. Olfactory is sensory only, and facial and glossopharyngeal are mixed nerves.
The neurons of motor pathway control?
- Voluntary muscles
- Stress reaction
- Involuntary muscles
- Organs and glands
Explanation: Answer reason: Motor pathways (somatic efferent system: corticospinal tract to lower motor neurons) innervate skeletal muscle and control voluntary movement.
Which cranial nerve innervates the lateral rectus muscle of the eye?
- Oculomotor
- Trochlear
- Abducens nerve
- Trigeminal
Explanation: Answer reason: The lateral rectus is innervated by cranial nerve VI, the abducens nerve (LR6).
Wrist drop caused by injury to which nerve?
- Axillary nerve
- Radial nerve
- Median nerve
- Ulnar nerve
Explanation: Answer reason: Wrist drop results from paralysis of wrist extensors, which are innervated by the radial nerve; radial nerve injury (e.g., in the spiral groove) causes inability to extend the wrist.
Lower lesions of the brachial plexuses cause?
- Erb-Duchenne Palsy
- Klumpkeplasy
- Both A and B
- None of above
Explanation: Answer reason: Lower trunk (C8–T1) brachial plexus injury causes Klumpke palsy; Erb-Duchenne palsy is from upper trunk (C5–C6).
The cell bodies of nerve fibres are situated in a swelling on posterior root called as?
- Anterior root ganglion
- Posterior root ganglion
- Anterior root
- Posterior root
Explanation: Answer reason: Sensory neuron cell bodies are located in the dorsal (posterior) root ganglion, a swelling on the posterior root of a spinal nerve.
Damaged to long thoracic nerve causes?
- Winged scapula
- Depressed scapula
- Laterally depressed scapula
- Medially depressed scapula
Explanation: Answer reason: The long thoracic nerve innervates the serratus anterior; injury causes serratus paralysis leading to medial winging of the scapula (winged scapula).
The primary function of the cerebellum is to?
- Process sensory input
- Coordinate movement and muscle tone
- Issue motor commands directly to muscles
- Relay reflex signals
Explanation: Answer reason: The cerebellum’s primary role is to coordinate voluntary movement, posture, balance, and muscle tone. It modulates motor activity rather than issuing direct motor commands or relaying reflexes.
Acalculia refers to?
- Inability to recognize sensory input
- Inability to do mathematical calculations
- Inequality in size of the pupils
- Visual aphasia
Explanation: Answer reason: Acalculia is the acquired inability to perform mathematical calculations, typically due to parietal lobe dysfunction.
Which brain structure is most responsible for our balance, posture and muscle tone?
- Cerebellum
- Pons
- Reticular system
- Medulla oblongata
Explanation: Answer reason: The cerebellum coordinates balance, posture, and muscle tone. The pons is a relay center, the reticular system regulates arousal, and the medulla controls vital autonomic functions.
Which of the following are nerve involve in hypoglossal, tongue movement for speech, sounds articulation and swallowing?
- CN IX
- CNXI
- CN XII
- CN IIX
Explanation: Answer reason: The hypoglossal nerve (cranial nerve XII) innervates the intrinsic and extrinsic muscles of the tongue, enabling movements for speech articulation and swallowing. CN IX is glossopharyngeal, CN XI is accessory, and CN IIX is not the hypoglossal nerve.
Oculomotor, extraocular eye movement, lid elevation, pupillary constrictions, lens shape: which cranial nerve is involved?
- CN 2
- CN 3
- CN 4
- CN5
Explanation: Answer reason: The oculomotor nerve (CN III) controls most extraocular movements, elevates the eyelid via levator palpebrae, and provides parasympathetic fibers for pupillary constriction and accommodation (lens shape).
Which of the following cranial nerves is related to the sense of smell?
- Abducens
- Hypoglossal
- Olfactory
- Trochlear
- Vagus
Explanation: Answer reason: The olfactory nerve (CN I) is the cranial nerve responsible for the sense of smell; the others control eye movements, tongue motor function, or autonomic/laryngeal functions.
Which type of cells phagocytize debris in the central nervous system?
- Ependymal cells
- Astrocytes
- Microglia
- Oligodendrocytes
Explanation: Answer reason: Microglia are the CNS resident macrophages that phagocytose cellular debris. Ependymal cells line ventricles and produce/assist CSF flow, astrocytes provide metabolic and structural support/BBB, and oligodendrocytes form myelin.
Damage to which cranial nerve results in inability to shrug and weak head movement?
- Glossopharyngeal nerve
- Vagus nerve
- Facial nerve
- Accessory nerve
Explanation: Answer reason: The spinal accessory nerve (CN XI) innervates the sternocleidomastoid and trapezius muscles, which are responsible for head rotation and shoulder elevation (shrugging). Damage causes weak head movement and inability to shrug.
Acoustic, Assess client's ability to hear loud and soft spoken words, watch tick test, which nerve involve?
- CN 8
- CN 6
- CN 7
- CN 9
Explanation: Answer reason: Hearing tests such as whisper/watch-tick assess the auditory function of the vestibulocochlear (acoustic) nerve, cranial nerve VIII.
Which of the following is the point at which an impulse is transmitted from one neuron to another neuron?
- Dendrite
- Glial cell
- Nerve center
- Synapse
- Terminal plate
Explanation: Answer reason: The junction where signals pass from one neuron to another is the synapse; dendrites receive input but are not the inter-neuronal junction, glial cells are support cells, nerve center is a group of neurons, and the terminal plate refers to the neuromuscular junction.
The physician has declared a client to be "brain dead." The nurse understands this means that the client has?
- No reflexes and no breathing.
- Slow reflexes and shallow breathing.
- No cortical functioning with some reflex breathing,
- Deep tendon reflexes only and no independent breathing.
Explanation: Answer reason: Brain death is the irreversible loss of all brain and brainstem function, including apnea. Spinal reflexes (e.g., deep tendon reflexes) may persist, so the best description is D.
Indicate the chemical mediator in the antinociceptive descending pathways?
- BETA-endorphin
- Met- and leu-enkephalin
- Dynorphin
- All of the above
Explanation: Answer reason: Beta-endorphin, enkephalins, and dynorphin are endogenous opioid peptides that mediate descending antinociceptive pathways.
Which synapses are involved in depression?
- Dopaminergic synapses
- Serotoninergic synapses
- Cholinergic synapses
- All of the above
Explanation: Answer reason: Serotonergic dysfunction is central to the pathophysiology of major depressive disorder, and first-line therapies (SSRIs) target serotonin synapses.
Which part of the brain is associated with hearing?
- Occipital lobe
- Frontal lobe
- Parietal lobe
- Temporal lobe
Explanation: Answer reason: Hearing is processed in the primary auditory cortex located in the temporal lobe; occipital is vision, parietal is somatosensory, and frontal is executive/motor.
The occipital lobe of the cerebrum is associated with which of the following?
- Vision
- Hearing
- Touching
- Smelling
Explanation: Answer reason: The occipital lobe is the primary visual processing center of the brain; hearing is temporal, touch is parietal, and smell involves the olfactory cortex.
Which of the following controls body temperature, sleep, and appetite?
- Adrenal glands
- Hypothalamus
- Pancreas
- Thalamus
- Thyroid gland
Explanation: Answer reason: The hypothalamus regulates key homeostatic functions including thermoregulation, hunger/satiety (appetite), and sleep-wake cycles. The other listed glands or structures do not primarily control this triad.
Which of the following is a substance that aids the transmission of nerve impulses to the muscles?
- Acetylcholine
- Cholecystokinin
- Deoxyribose
- Oxytocin
- Prolactin
Explanation: Answer reason: Acetylcholine is the primary neurotransmitter at the neuromuscular junction, transmitting nerve impulses to skeletal muscle. The other choices are hormones or a sugar and do not mediate neuromuscular transmission.
Second-order pain is?
- Sharp, well-localized pain
- Dull, burning pain
- Associated with fine myelinated A-delta fibers
- Effectively reduced by non-narcotic analgesics
Explanation: Answer reason: Second (slow) pain is dull, burning, and poorly localized, mediated by C fibers; sharp, well-localized pain and A-delta fibers describe first pain, and second pain is not specifically best relieved by non-narcotics.
Indicate the neurons, which are located in the locus ceruleus or the lateral tegmental area of the reticular formation?
- Dopaminergic
- Serotoninergic
- Nonadrenergic
- Gabaergic
Explanation: Answer reason: The locus coeruleus and lateral tegmental area are major sources of noradrenergic (norepinephrine) neurons in the brain; dopaminergic neurons are in substantia nigra/VTA, serotonergic in raphe nuclei, and GABAergic are not characteristic of these nuclei.
Which condition is characterized by an abnormal accumulation of cerebrospinal fluid in the brain?
- Hydrocephalus
- Encephalocele
- Cephalohematoma
- Microcephaly
Explanation: Answer reason: Hydrocephalus is defined by excessive cerebrospinal fluid accumulation within the ventricles of the brain. Encephalocele is a herniation of brain tissue, cephalohematoma is a subperiosteal scalp bleed, and microcephaly is abnormally small head size.
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