Pharmacology Practice Test 60
Pharmacology NCLEX Practice Test
Pharmacology is a key topic within the NCLEX test plan, located under Nursing Science → Clinical Foundations → Pharmacology. This section details drug mechanisms, safe administration, and patient education across nursing specialties. Each test contains 50 questions designed to mirror the difficulty and variety of the real exam.
This is the 60th part of the Pharmacology series. To explore all practice tests under this topic, use the “Back to Main Topic” button at the end of the page.
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In the Pharmacology Study Cards section, shared by real NCLEX candidates, you’ll find concise summaries and high-yield insights related to the most tested concepts. It’s a perfect space to reinforce challenging topics and sharpen your recall through quick, focused repetitions. Short, powerful, and repeatable!
Pharmacology Practice Test 60
A patient is admitted to the hospital with an acute gout attack. The nurse expects that which medication will be ordered to treat acute gout?
- Colchicine
- Allopurinol
- Probenecid
- Sulfinpyrazone
Explanation: Answer reason: This medication inhibits neutrophil chemotaxis and activation, decreasing inflammation and pain during an acute flare. In contrast, xanthine oxidase inhibitors and uricosurics are primarily for long-term urate lowering and are not first-line to start for immediate flare control. Starting chronic urate-lowering therapy during an active flare can complicate management and does not provide rapid symptom relief.
A nurse is teaching a client who has a prescription for a drug that has a receptor agonist effect. Which of the following information should the nurse include in the teaching?
- This will increase the effects of normal cellular functions
- This prevents cells in your body from performing certain actions
- This prevents hormones in your body from attaching to cell receptor sites
- This minimizes the risk that the medications you take will become toxic
Explanation: Answer reason: This leads to increased receptor-mediated cellular activity and therefore amplifies normal physiologic effects in the target tissue. In contrast, blocking cellular actions or preventing hormones from binding describes antagonism, not agonism. Toxicity risk is related to dose, metabolism, and therapeutic index rather than the definition of an agonist effect.
A nurse is preparing to administer a drug to a client. In which of the following sections of a drug handbook should the nurse look to determine if the client can receive the drug?
- Adverse effects
- Contraindications
- Implementation
- Black box warning
Explanation: Answer reason: The contraindications section lists absolute and relative reasons a patient should not receive a medication (e.g., allergy, specific comorbidities, pregnancy status, or dangerous drug–drug interactions). This directly answers whether the client can receive the drug before administration. Adverse effects describes potential unwanted reactions after a drug is given, not whether it is permitted to give it in the first place.
A nurse is caring for a client who is receiving nitroglycerin iv and is switching to the oral form of the drug. The nurse should identify that the oral dose will be higher than the iv dose for which of the following reasons?
- The iv form crosses the blood-brain barrier
- The oral form has a decreased half life
- The oral form has decreased bioavailability because of the first pass effect
- The oral form has increased rate of excretion
Explanation: Answer reason: Nitroglycerin undergoes extensive hepatic first-pass metabolism, so a smaller fraction of an oral dose reaches the bloodstream compared with IV administration, which is 100% bioavailable. Therefore, a higher oral dose is typically required to achieve a similar systemic effect. Differences in blood-brain barrier penetration are not the key determinant of dose conversion here, and changes in half-life or renal excretion do not explain the predictable need for higher dosing with this medication’s oral route.
When taking Digoxin, low levels of what can cause toxicity?
- Potassium
- Calcium
- Sodium
- Magnesium - A. potassium
Explanation: Answer reason: Digoxin competes with potassium at the Na+/K+ ATPase pump, so decreased serum potassium increases digoxin binding and its pharmacologic effect. This amplifies the risk of toxicity manifestations such as dysrhythmias, GI symptoms, and visual changes even at therapeutic digoxin levels. Clinically, hypokalemia from loop/thiazide diuretics is a classic precipitant of digoxin toxicity, making electrolyte monitoring essential. In contrast, low sodium is not a primary driver of digoxin toxicity, and calcium abnormalities relate more to arrhythmia risk than the key binding mechanism tested here. Hypomagnesemia can contribute to arrhythmias, but hypokalemia is the most directly associated electrolyte trigger for digoxin toxicity.
When taking Nitroglycerine (transdermal), you should have how many hours nitrate free each day?
- 1-2 hours
- 5-10 hours
- 3-4 hours
- 10-12 hours
Explanation: Answer reason: Continuous exposure to nitrates leads to tolerance, reducing antianginal effectiveness. Transdermal nitroglycerin is therefore scheduled with a daily nitrate-free interval to restore responsiveness and maintain symptom control. A 10–12 hour nitrate-free period is the standard approach used with patches (e.g., remove at night if daytime angina prophylaxis is needed). Shorter intervals (such as 1–4 hours) are typically insufficient to prevent tolerance from developing.
Angiotensin II receptor agents medications usually end in?
- Sa-tan
- Se
- Olol
- Pril
- Sa-rtan
Explanation: Answer reason: Angiotensin II receptor blockers (ARBs) follow a consistent drug-name stem that helps quickly identify the class and anticipate effects. The “-sartan” ending denotes ARBs such as losartan, valsartan, and candesartan, which block angiotensin II at the AT1 receptor to lower blood pressure and reduce aldosterone-mediated sodium retention. By contrast, “-pril” indicates ACE inhibitors, and “-olol” indicates beta blockers, so selecting those would misclassify the medication class. Recognizing stems supports safe medication identification and prediction of class-specific adverse effects (e.g., hyperkalemia) and contraindications (e.g., pregnancy).
A client with a subdural hematoma becomes restless and confused, with dilation of the ipsilateral pupil. The physician orders mannitol for which of the following reasons?
- To reduce intracranial pressure
- To prevent acute tubular necrosis
- To promote osmotic diuresis to decrease ICP
- To enhance blood flow into the vascular system to increase blood pressure
Explanation: Answer reason: This reduces cerebral edema and lowers intracranial pressure, which is urgently needed with signs of increased ICP such as altered mental status and an ipsilateral dilated pupil. The key tested mechanism is osmotic fluid shift and diuresis rather than a nonspecific statement. A common distractor is acute tubular necrosis prevention, but mannitol is used to lower ICP and, if overused or in renal failure, can actually worsen fluid/electrolyte problems.
Alteration of which laboratory finding represents the achievement of a therapeutic goal for heparin administration?
- Prothrombin time (PT)
- Fibrin split products
- Platelet count
- Partial thromboplastin time (PTT)
Explanation: Answer reason: Therapeutic anticoagulation is therefore monitored by targeting an elevated aPTT (or anti-Xa level), indicating adequate inhibition of thrombin and factor Xa activity. PT is mainly used to monitor warfarin therapy via the extrinsic pathway, so it does not best represent heparin effect. Platelet count is tracked to detect heparin-induced thrombocytopenia rather than to confirm therapeutic anticoagulation, and fibrin split products are not standard for routine heparin titration.
A patient is having a migraine attack. The nurse should know that which drugs are used to treat migraine attacks?
- Triptans
- Anticonvulsants
- Tricyclic antidepressants
- Beta-adrenergic blockers
Explanation: Answer reason: This option fits because these agents (5-HT1B/1D agonists) are first-line, migraine-specific drugs taken at attack onset to stop headache progression and associated symptoms. Several other listed drugs are primarily used for migraine prophylaxis rather than aborting an active attack. A common trap is selecting beta-blockers or tricyclic antidepressants, which help reduce attack frequency but are not the standard immediate rescue medications for an ongoing migraine.
The nurse suspects that a patient who is experiencing facial grimacing, involuntary upward eye movement, and muscle spasms of the tongue and face may have which condition?
- Akathisia
- Acute dystonia
- Tardive dyskinesia
- Pseudoparkinsonism
Explanation: Answer reason: g., antipsychotics, metoclopramide). Sustained involuntary muscle contractions cause facial/tongue spasms and oculogyric crisis (upward deviation of the eyes), which matches the presentation. Akathisia is primarily an inner restlessness with inability to sit still rather than focal spasms. Tardive dyskinesia tends to be late-onset, with choreoathetoid lip-smacking and tongue movements rather than abrupt painful dystonic posturing.
A patient asks the nurse to explain how antipsychotic drugs work to make him feel better. The nurse understands that antipsychotics act in which way?
- Blocking actions of dopamine
- Blocking actions of epinephrine
- Promoting prostaglandin synthesis
- Enhancing the action of gamma-aminobutyric acid
Explanation: Answer reason: This mechanism is central to both first-generation agents and contributes (along with serotonin effects) to many second-generation agents. Epinephrine blockade is not a therapeutic mechanism for psychosis and would more likely relate to cardiovascular effects. Prostaglandin synthesis is associated with NSAIDs, and enhancing GABA is characteristic of benzodiazepines used for anxiety/seizure control rather than antipsychotic treatment.
An antipsychotic agent, fluphenazine (Prolixin), is ordered for a patient with psychosis. The nurse understands that this agent can lead to extrapyramidal symptoms that may be treated with which medication?
- Quetiapine (Seroquel)
- Aripiprazole (Abilify)
- Benztropine (Cogentin)
- Chlorpromazine (Thorazine)
Explanation: Answer reason: Anticholinergic agents restore the dopamine–acetylcholine balance and reduce acute dystonia, parkinsonism, and akathisia. Benztropine is a standard anticholinergic used for treating these medication-induced movement disorders. Switching to an atypical antipsychotic can lower future EPS risk, but it is not the immediate symptomatic treatment being tested here.
Which of the following is a potassium-sparing diuretic?
- Furosemide
- Spironolactone
- Hydrochlorothiazide
- Bumetanide
Explanation: Answer reason: Potassium-sparing diuretics act in the distal nephron to reduce sodium reabsorption without increasing potassium loss. This medication is an aldosterone antagonist, so it decreases potassium excretion and can raise serum potassium. In contrast, loop diuretics like furosemide and bumetanide and thiazides like hydrochlorothiazide typically cause potassium wasting and can lead to hypokalemia. Clinically, monitoring for hyperkalemia is essential when using this class, especially with renal impairment or ACE inhibitors/ARBs.
Which of the following drugs has a therapeutic effect that increases cardiac output and slows heart rate?
- Heparin
- Alprazolam
- Digoxin
- Levothyroxine
Explanation: Answer reason: It also enhances vagal tone at the AV node, producing a negative chronotropic effect and slowing the heart rate (and ventricular response in atrial fibrillation). This combination—positive inotropy with heart-rate slowing—is characteristic of cardiac glycosides. Heparin is an anticoagulant without direct effects on inotropy or AV nodal conduction, making it an unsafe match for the described therapeutic goal. Levothyroxine tends to increase heart rate and myocardial oxygen demand, which is opposite of the rate-slowing effect described.
Which of the following diuretics inhibits sodium reabsorption in the kidneys while saving K+ and Hydrogen ions?
- Spironolactone
- Furosemide
- Hydrochlorothiazide
- Bumetanide
Explanation: Answer reason: Spironolactone is an aldosterone antagonist that blocks aldosterone-driven ENaC/Na⁺-K⁺ exchange effects, so Na⁺ is excreted while K⁺ and H⁺ are retained. Loop diuretics (furosemide, bumetanide) and thiazides (hydrochlorothiazide) increase distal sodium delivery and typically increase K⁺ and H⁺ losses, causing hypokalemia and metabolic alkalosis. Therefore the described mechanism best matches an aldosterone antagonist.
The nurse is preparing a child for transport to the operating room for an emergency appendectomy. The anesthesiologist prescribes atropine sulfate (Atropine), IM STAT. What is the primary purpose for administering this drug to the child at this time?
- Decrease the oral secretions
- Reduce the child's anxiety
- Potentiate the opioid effects
- Prevent possible peritonitis
Explanation: Answer reason: In a child being transported for emergency surgery, the priority pharmacologic goal is to dry secretions to reduce aspiration risk and improve airway management. Anxiety reduction is typically achieved with sedatives/anxiolytics, not atropine. Preventing peritonitis is addressed by prompt surgery and antibiotics rather than an antimuscarinic agent.
When caring for a client on digoxin (Lanoxin) therapy, the nurse knows to alert for digoxin (Lanoxin) toxicity. Which finding would predispose this client to developing digoxin toxicity?
- Low serum sodium level
- High serum sodium level
- Low serum potassium level
- High serum potassium level
Explanation: Answer reason: With lower potassium, digoxin binds more readily, amplifying its electrophysiologic effects and increasing the risk of dysrhythmias and other toxicity manifestations. This is a classic, high-yield predisposing factor, especially in clients also taking potassium-wasting diuretics. By contrast, sodium abnormalities are not a primary driver of digoxin binding and do not predict toxicity as reliably as potassium deficits.
Which legal substance's street name is abused by some people and can lead to anorexia, tics, insomnia, nausea and mood changes during withdrawal?
- Whippets
- African salad
- Buttons
- Eve
Explanation: Answer reason: “Whippets” refers to nitrous oxide canisters, a legal product (whipped-cream chargers) that is commonly abused recreationally. Misuse can produce neuropsychiatric effects and GI symptoms, and stopping heavy use may be associated with irritability and mood changes. The other options are not standard, widely accepted street names for a common legal inhalant matching this presentation in typical exam contexts.
The nurse is developed a teaching plan for a client prescribed spironolactone. On which psychosocial side effect of the medication should the nurse base the teaching plan?
- Edema
- Hair loss
- Weight loss
- Decreased libido
Explanation: Answer reason: A decreased libido is a recognized effect and is commonly addressed in patient teaching because it can affect adherence and psychosocial well-being. Edema is typically an indication for use rather than a side effect expected to worsen with therapy. Hair loss and weight loss are not characteristic teaching points compared with spironolactone’s sexual and reproductive adverse effects (e.g., gynecomastia, menstrual irregularities, reduced libido).
All of the following antidiabetic drug can cause hypoglycemia, EXCEPT?
- Insulin
- Glimepiride
- Metformin
- Gliclazide
Explanation: Answer reason: Insulin directly lowers blood glucose and can readily precipitate hypoglycemia if dose, intake, or activity are mismatched. Sulfonylureas such as glimepiride and gliclazide stimulate pancreatic insulin release and therefore carry a significant hypoglycemia risk, especially in older adults or with missed meals. In contrast, metformin mainly reduces hepatic gluconeogenesis and improves insulin sensitivity, so it rarely causes hypoglycemia when used alone (risk rises mainly when combined with insulin/secretagogues or with poor oral intake).
Which of the following anti fungal agent has only topical action?
- Fluconazole
- Ketoconazole
- Itraconazole
- Clotrimazole
Explanation: Answer reason: Clotrimazole is an imidazole commonly used as topical or intravaginal therapy for superficial candidiasis and dermatophyte infections, making it the best match for “only topical action” in typical exam framing. In contrast, fluconazole and itraconazole are standard systemic azoles used orally for mucocutaneous and invasive fungal infections. Ketoconazole historically had oral use but is limited due to hepatotoxicity and endocrine adverse effects, so it is not considered “only topical.”.
Clexane is used for ...?
- Blood clot
- Malaria
- Blood pressure
- Anemia
Explanation: Answer reason: Clinically it is used for prevention and management of venous thromboembolism (DVT/PE) and as part of therapy in acute coronary syndromes. The stem asks the primary indication category, which aligns with preventing/treating clot formation rather than affecting infection, blood pressure, or red-cell production. Malaria and anemia are treated with antiparasitics and hematinics respectively, not anticoagulants, and antihypertensives address blood pressure via vascular/cardiac mechanisms rather than coagulation.
Which of the following is a beta-blocker?
- Atenolol
- Ibuprofen
- Amoxicillin
- Paracetamol
Explanation: Answer reason: Atenolol is a cardioselective β1-blocker and is a classic example of this drug class. Ibuprofen and paracetamol are analgesic/antipyretic agents (NSAID and non-opioid analgesic, respectively), not adrenergic blockers. Amoxicillin is a beta-lactam antibiotic, which is unrelated to β-receptor blockade.
Acetylcholine is not used commercially because?
- Long duration of action
- Costly
- Rapidly destroyed in the body
- Crosses blood brain barrier
Explanation: Answer reason: Acetylcholine is hydrolyzed very quickly by acetylcholinesterase (and plasma cholinesterases), so its actions are extremely short-lived and difficult to control clinically. This makes it impractical for routine commercial/therapeutic use compared with more stable cholinergic agonists (e.g., bethanechol, carbachol). “Long duration of action” is the opposite of the true property and would generally make a drug more, not less, practical in many settings. In addition, acetylcholine is a quaternary ammonium compound and does not meaningfully cross the blood–brain barrier, so that option is incorrect.
Metronidazole is used to treat?
- Diabetes
- Diarrhea
- Cough
- Vomit
Explanation: Answer reason: It is a standard therapy for protozoal diarrhea such as giardiasis and amoebiasis, and it is also used for anaerobic intra-abdominal infections. In contrast, it has no role in treating metabolic diseases like diabetes, and it is not a primary medication for nonspecific cough. While vomiting can be a symptom of infection or a drug adverse effect, it is not an indication that metronidazole specifically targets.
Morphine is?
- NSAID
- Opioid analgesic
- Antibiotic
- Antifungal
Explanation: Answer reason: This receptor activity decreases neurotransmitter release and alters pain perception and response, making it appropriate for moderate to severe pain. NSAIDs work mainly by inhibiting cyclooxygenase and prostaglandin synthesis and are a different drug class with different indications and adverse effects. Antibiotics and antifungals target microorganisms and have no role in directly treating pain.
A patient has an elevated prothrombin (PT) time. Which medication should the Nurse consider as a possible cause of the elevated PT Time?
- Rifampin
- Vitamin K
- Birth control pills
- Phenytoin (Dilantin)
Explanation: Answer reason: This medication can interfere with vitamin K status (e.g., via hepatic enzyme effects and reduced vitamin K–dependent clotting factor activity), leading to prolonged PT and bleeding tendency. In contrast, vitamin K would be expected to shorten PT by restoring gamma-carboxylation of clotting factors. Oral contraceptives more commonly increase thrombotic risk rather than prolong PT.
A patient taking propylthiouracil should be instructed to reduce dietary sources of?
- Vitamin k
- Iodine
- Potassium
- Iron
Explanation: Answer reason: A high-iodine diet can counteract antithyroid therapy by providing more raw material for hormone production, reducing medication effectiveness. Therefore, counseling to limit iodine-rich foods and supplements (e.g., seaweed/kelp, iodized salt, some contrast-containing products) supports better control of hyperthyroidism. Vitamin K, potassium, and iron do not directly oppose the drug’s mechanism of lowering thyroid hormone production.
Diclofenac used for ...?
- Appetite
- Cough
- Allergy
- Pain
Explanation: Answer reason: Lower prostaglandins decreases inflammation, pain, and fever, making it commonly used for musculoskeletal pain, arthritis, and dysmenorrhea. It is not an antitussive, antihistamine, or appetite stimulant, so those options do not match its primary therapeutic effect. A key exam point is that its analgesic effect is coupled with anti-inflammatory action, distinguishing it from medications used for cough or allergy symptoms.
Which antibiotic is most associated with Gray Baby syndrome?
- Penicillin
- Gentamicin
- Chloramphenicol
- Tetracycline
Explanation: Answer reason: Gray baby syndrome is a toxic reaction in neonates due to impaired hepatic glucuronidation and reduced renal clearance, leading to drug accumulation. This toxicity causes ashen-gray cyanosis, hypothermia, vomiting, abdominal distension, and cardiovascular collapse. The antibiotic classically implicated is chloramphenicol because newborns cannot adequately metabolize and eliminate it. A common distractor is tetracycline, which is instead associated with tooth discoloration and inhibition of bone growth in children. Recognition of this association is key for avoiding use in neonates and for monitoring if exposure occurs.
Which of the following drugs is a selective serotonin reuptake inhibitor?
- Diazepam
- Haloperidol
- Paroxetine
- Amitriptyline
- Phenelzine
Explanation: Answer reason: Among the listed medications, this mechanism and drug class match an SSRI. By contrast, diazepam is a benzodiazepine (GABA-A potentiation), haloperidol is a typical antipsychotic (D2 antagonism), amitriptyline is a tricyclic antidepressant, and phenelzine is an MAOI. Therefore the SSRI choice is the one in the paroxetine/sertraline/fluoxetine family rather than sedatives, antipsychotics, TCAs, or MAOIs.
Which drug is used as an Anti-Anxiety drug?
- Warfarin
- Diazepam
- Latanoprost
- Hydralazine
Explanation: Answer reason: Among the options, diazepam is a benzodiazepine commonly used for acute anxiety and related conditions. Warfarin is an anticoagulant, latanoprost is a prostaglandin analog for glaucoma, and hydralazine is a vasodilator for hypertension—none treat anxiety. Key nursing consideration with benzodiazepines is CNS/respiratory depression risk, especially with other sedatives, and dependence potential with prolonged use.
Which drug is a loop diuretic?
- Furosemide
- Hydrochlorothiazide
- Spironolactone
- Amiloride
Explanation: Answer reason: The option that matches this class is the prototypical loop agent used for edema and acute pulmonary edema due to its strong natriuretic effect. In contrast, hydrochlorothiazide is a thiazide diuretic acting in the distal convoluted tubule, while spironolactone and amiloride are potassium-sparing diuretics with weaker diuretic effect. Recognizing drug-class prototypes is a core pharmacology skill for anticipating effects and adverse reactions (e.g., hypokalemia with loop agents).
Which drug is an antihypertensive?
- Lisinopril
- Aspirin
- Paracetamol
- Loratadine
Explanation: Answer reason: This drug is an ACE inhibitor that decreases angiotensin II formation and aldosterone release, leading to vasodilation and reduced blood pressure. By contrast, aspirin is an antiplatelet/analgesic, paracetamol is an analgesic/antipyretic, and loratadine is a second-generation antihistamine—none are primarily used to treat hypertension. The mechanism and standard clinical indication match blood-pressure control.
Metformin is a medication primarily prescribed for the management of which condition?
- Asthma
- Type 2 Diabetes
- Heart failure
Explanation: Answer reason: Metformin is a first-line oral antihyperglycemic agent used to improve glycemic control in adults with insulin resistance. It primarily decreases hepatic gluconeogenesis and increases peripheral insulin sensitivity, lowering fasting and postprandial glucose without directly stimulating insulin release. This mechanism aligns with the pathophysiology of type 2 diabetes, where insulin resistance is central. Asthma is treated with bronchodilators and anti-inflammatory agents, and heart failure management relies on diuretics and guideline-directed cardiac medications rather than glucose-lowering therapy.
Which effect does the nurse expect to see in a patient receiving hydrocortisone (Solu-Cortef)?
- Increase in inflammatory leukocyte function
- Reduction of scar tissue formation
- Renal excretion of sodium
- Hypotension
Explanation: Answer reason: Hydrocortisone therefore can blunt tissue repair and lead to delayed healing with less scar tissue development. In contrast, corticosteroids decrease (not increase) leukocyte migration and inflammatory function, producing immunosuppression. They also have mineralocorticoid activity that promotes sodium and water retention and can raise blood pressure rather than causing hypotension or sodium excretion.
Bisacodyl is used as?
- Painkiller
- Laxative
- Antacid
- Sedative
Explanation: Answer reason: This makes it appropriate for treating constipation and for bowel preparation before procedures. The other options do not match its pharmacologic class or primary clinical effect; for example, an antacid neutralizes gastric acid rather than stimulating intestinal motility. Key safety considerations include avoiding routine overuse due to risk of cramping, diarrhea, and electrolyte imbalance.
In addition to oxygen therapy & rest, which of the following medications is included in the plan of treatment for a CHF client that increases contractility of the heart?
- Aldactone (Spironolactone)
- Lanoxin (Digoxin)
- Lasix (Furosemide)
- Diuril (Chlorothiazide)
Explanation: Answer reason: In congestive heart failure, this can improve cardiac output and help reduce symptoms in selected patients, especially when there is concurrent atrial fibrillation requiring rate control. Spironolactone is an aldosterone antagonist that improves outcomes mainly by neurohormonal blockade and mild diuresis, not by increasing contractility. Furosemide and chlorothiazide are diuretics that reduce preload and congestion but do not directly increase the strength of myocardial contraction.
Diclofenac is use for ...?
- Allergy
- Cough
- Appetite
- Pain
Explanation: Answer reason: Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX) enzymes, decreasing prostaglandin synthesis. This leads to reduced inflammation and analgesia, so its primary clinical use is for pain (often with associated inflammation, e.g., musculoskeletal pain, arthritis, dysmenorrhea). It is not an antitussive, antihistamine, or appetite stimulant, making those options inconsistent with its pharmacologic class. A key safety consideration is GI irritation/bleeding risk and renal effects typical of NSAIDs, reinforcing it as an analgesic/anti-inflammatory rather than a symptom-specific drug like a cough suppressant.
Omeprazole is used for?
- Couch
- Fever
- Ulcer
- Pneumonia
Explanation: Answer reason: Acid reduction promotes healing of peptic ulcers and is a key component of therapy for GERD and H. pylori–associated ulcer disease (as part of combination regimens). Fever and pneumonia are not conditions treated with acid-suppressing therapy, and cough is not a primary indication. Therefore the option that matches the drug’s therapeutic use is peptic ulcer disease.
A depressed client is seen at the mental health center for follow-up after an attempted suicide 1 week ago. She has taken phenelzine sulfate (Nardil), a monoamine oxidase (MAO) inhibitor, for 7 straight days. She states that she is not feeling any better. The nurse explains that the drug must accumulate to an effective level before symptoms are totally relieved. Symptom relief is expected to occur within?
- 10 days
- 2-4 weeks
- 2 months
- 3 months
Explanation: Answer reason: After only 7 days, lack of symptom improvement is expected and does not indicate treatment failure if adherence is adequate. The 2–4 week window best matches standard onset expectations for antidepressant response. Ten days is usually too soon for full therapeutic benefit, while 2–3 months is longer than the typical initial response timeframe used to counsel patients and monitor early treatment effect.
Which one of the following antifungal medication has the highest risk of drug induced renal toxicity?
- Ketoconazole
- Fluconazole
- Amphotericin
- Itraconazole
Explanation: Answer reason: Clinically this can present with rising creatinine and electrolyte wasting, especially hypokalemia and hypomagnesemia, which requires close monitoring during therapy. Among common systemic antifungals, the azoles (ketoconazole, fluconazole, itraconazole) are more strongly linked to hepatotoxicity and drug–drug interactions than severe intrinsic renal toxicity. Therefore the option with the highest renal toxicity risk is the polyene agent.
Which anti TB drug cause orange coloured urine? (NEET)?
- Pyrazinamide
- Rifampicin
- Streptomycin
- Isoniazide
Explanation: Answer reason: This effect is benign but clinically important for patient counseling to prevent alarm and to warn about possible staining of contact lenses. Other first-line TB drugs have different signature toxicities: isoniazid is linked to peripheral neuropathy/hepatotoxicity, pyrazinamide to hyperuricemia/hepatotoxicity, and streptomycin to ototoxicity/nephrotoxicity. Therefore, the drug most specifically associated with orange-colored urine is the rifamycin agent.
Which antibiotic is a fluoroquinolone?
- Ciprofloxacin
- Erythromycin
- Vancomycin
- Azithromycin
Explanation: Answer reason: Ciprofloxacin is a prototypical fluoroquinolone commonly used for gram-negative infections (e.g., some UTIs and GI pathogens). In contrast, erythromycin and azithromycin are macrolides, and vancomycin is a glycopeptide active mainly against gram-positive organisms. Recognizing drug class names (often ending in “-floxacin”) helps prevent mix-ups and anticipate class-specific adverse effects (e.g., tendinopathy, QT prolongation).
Mala-D is taken for _______?
- 7 days
- 14 days
- 21 days
- 30 days
Explanation: Answer reason: Mala-D is a combined oral contraceptive brand that follows this standard regimen of 21 active pills per cycle. This makes the 21-day duration the best match among the choices. Options like 7 or 14 days do not correspond to standard combined pill cycles, and 30 days is not the conventional active-pill course length.
Which of the following drugs is a glucocorticoid?
- Dexamethasone
- Furosemide
- Lisinopril
- Metformin
Explanation: Answer reason: Dexamethasone is a synthetic glucocorticoid with minimal mineralocorticoid activity and is commonly used for conditions like cerebral edema, severe inflammation, and as part of antiemetic regimens. In contrast, furosemide is a loop diuretic, lisinopril is an ACE inhibitor, and metformin is a biguanide antihyperglycemic—none are corticosteroids. Therefore, the only option that fits the drug class asked is the corticosteroid listed.
Which drug is an angiotensin II receptor blocker?
- Losartan
- Lisinopril
- Metoprolol
- Furosemide
Explanation: Answer reason: Drugs in this class characteristically end in “-sartan,” and this option matches that hallmark. In contrast, “-pril” drugs such as the ACE inhibitor listed act upstream by inhibiting conversion of angiotensin I to II and increasing bradykinin, while the beta-blocker and loop diuretic work through entirely different mechanisms. Recognizing suffix-based pharmacologic classes is a high-yield way to distinguish antihypertensive drug types on exams.
Drug used for Asthma?
- Salbutamol
- Codein
- Amoxicillin
- Oxytocin
Explanation: Answer reason: This option is a short-acting beta-2 agonist that produces quick bronchodilation and is used as a rescue inhaler in acute wheeze/bronchospasm. In contrast, an opioid antitussive can worsen respiratory status by depressing ventilation and is not an asthma treatment. The antibiotic and uterotonic have no role in relieving bronchospasm or controlling asthma inflammation.
Atropine is used in?
- Emergency
- TB
- Ulcer
- Worm
Explanation: Answer reason: Clinically, it is used in acute/emergency settings such as symptomatic bradycardia and as part of management for organophosphate poisoning (with other therapies) to counter muscarinic excess. These indications are time-sensitive and align with emergency care use rather than chronic infectious disease treatment. TB and worm infestations require antimicrobial/anthelmintic agents, and peptic ulcer disease is primarily managed with acid suppression and H. pylori eradication rather than anticholinergics.
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