Pathology Practice Test 14
Pathology NCLEX Practice Test
Pathology is a key topic within the NCLEX test plan, located under Nursing Science → Clinical Foundations → Pathology. This section connects disease mechanisms to clinical manifestations and nursing priorities for safe patient care. Each test contains 50 questions designed to mirror the difficulty and variety of the real exam.
This is the 14th part of the Pathology series. To explore all practice tests under this topic, use the “Back to Main Topic” button at the end of the page.
Continue Learning
In the Pathology Study Cards section, shared by real NCLEX candidates, you’ll find concise summaries and high-yield insights related to the most tested concepts. It’s a perfect space to reinforce challenging topics and sharpen your recall through quick, focused repetitions. Short, powerful, and repeatable!
Pathology Practice Test 14
The nurse knows which burn involves the entire thickness of the skin?
- First degree.
- Second degree.
- Third degree.
- Fifth degree.
Explanation: Answer reason: Full-thickness burns destroy both the epidermis and the entire dermis, often extending into subcutaneous tissue, which defines a third-degree burn. This degree typically presents with leathery, charred, or waxy skin and may be relatively painless due to nerve ending destruction. First-degree burns are limited to the epidermis, and second-degree burns are partial-thickness involving epidermis plus part of the dermis with blistering and significant pain. “Fifth degree” is not part of the standard clinical burn-depth classification used for degree-based descriptions.
A client has been diagnosed with late-stage Lyme disease. The nurse anticipates that the client may exhibit which of the following?
- Arthritis
- Lung abscess
- Renal failure
- Sterility
Explanation: Answer reason: This results from ongoing immune-mediated inflammation and can present months after the initial infection. Pulmonary abscess is not a typical complication of Lyme disease and would suggest a different bacterial process. Renal failure and sterility are also not characteristic late manifestations compared with joint and neurologic findings.
A nurse is reviewing the causes of ulcerative colitis with a client. Which factor is believed to cause ulcerative colitis?
- Acidic diet
- Altered immunity
- Chronic constipation
- Emotional stress
Explanation: Answer reason: This immune-mediated process helps explain chronic relapsing symptoms and the association with extraintestinal inflammatory manifestations. Diet composition and constipation are not considered causal mechanisms, though diet can influence symptom severity. Psychological stress can exacerbate flares via neuroendocrine-immune effects, but it is not regarded as the underlying cause.
Which diagnostic criterion is considered a major Jones criterion for acute rheumatic fever?
- Carditis
- Prolonged PR interval
- Low-grade fever
- Previous heart disease
Explanation: Answer reason: Major criteria represent characteristic inflammatory manifestations of the disease, particularly involving joints, heart, skin, and the nervous system. Cardiac involvement is a defining manifestation because autoimmune-mediated inflammation can affect endocardium, myocardium, and pericardium and is a key driver of morbidity. In contrast, prolonged PR interval and fever are minor criteria and are less specific, while prior heart disease is not part of the Jones criteria used to establish an acute diagnosis.
When inspecting the palms of a child, with which rash would the nurse expect to find no changes?
- Coxsackie virus
- Measles
- Rocky Mountain spotted fever
- Syphilis
Explanation: Answer reason: Therefore, inspection of the palms would be expected to show no rash-related changes. In contrast, coxsackie (hand-foot-mouth disease), Rocky Mountain spotted fever, and secondary syphilis commonly involve the palms/soles, making palm findings expected in those conditions. The key discriminating principle is whether the illness characteristically affects palmar/plantar skin.
The success of treatment of local radiation depends upon?
- Extent of tissue injury.
- Rate of therapy.
- The designated area.
- Use of systemic medications.
Explanation: Answer reason: Local radiation therapy works by delivering a therapeutic dose precisely to the target tissue while minimizing exposure to surrounding healthy structures. Treatment success therefore relies heavily on accurate localization and field design so the intended lesion receives the planned dose distribution. If the target area is not correctly designated, the tumor may be underdosed and adjacent normal tissue may be overdosed, reducing efficacy and increasing complications. Factors like tissue injury extent or systemic medications can affect tolerance and side effects, but they are not the primary determinant of whether local radiation effectively treats the intended site.
The most serious and irreversible adverse effects of lead intoxication affect which system?
- Central nervous system (CNS)
- Hematologic system
- Renal system
- Respiratory system
Explanation: Answer reason: This can produce permanent cognitive impairment, learning disabilities, behavioral problems, and encephalopathy—effects that are the most clinically serious and often irreversible. While lead also causes hematologic toxicity (impaired heme synthesis leading to anemia) and can injure kidneys, these are generally less defining for long-term irreversible outcomes compared with neurodevelopmental damage. Therefore, the system with the most serious irreversible effects is the CNS.
The nurse is teaching the student nurse about muscular dystrophy. The student nurse asks which form of muscular dystrophy is most common. Which response is most accurate?
- Duchenne’s
- Becker’s
- Limb girdle
- Myotonic
Explanation: Answer reason: It typically presents in early childhood with progressive proximal muscle weakness, Gowers sign, and later cardiopulmonary involvement, reflecting near-absent dystrophin. Becker muscular dystrophy is also X-linked but is less common and generally milder with later onset due to partially functional dystrophin. Limb-girdle and myotonic dystrophies have different inheritance patterns and clinical courses and are not the most common form overall in pediatrics.
Which type of burn is very painful and heals without scarring or contractures in approximately 7 to 14 days?
- First degree.
- Third degree.
- Fourth degree.
- Deep second degree.
Explanation: Answer reason: Superficial (epidermal) burns preserve dermal structures, so re-epithelialization occurs quickly and healing is expected within about 1–2 weeks without scarring or contractures. These burns are typically very painful because sensory nerve endings in the dermis remain intact and are irritated by inflammation. In contrast, third- and fourth-degree burns destroy deeper tissues and are often less painful initially due to nerve destruction and they heal with significant scarring and functional loss. Deep second-degree burns extend further into the dermis and commonly take longer to heal and are more likely to scar or contract.
Which client is most likely to develop ankylosing spondylitis?
- White female, age 16, with knee pain
- Black male, age 50, with hip pain
- Asian female, age 70, with chest pain
- White male, age 23, with back pain
Explanation: Answer reason: The classic presenting symptom is inflammatory low back pain due to sacroiliitis, often with morning stiffness and improvement with activity. The demographic and symptom pattern in this option aligns with the highest pretest probability for the disease. In contrast, isolated knee pain in a teen or new chest pain in an elderly client is more suggestive of alternative musculoskeletal or cardiopulmonary conditions rather than early axial spondyloarthritis. Age 50 hip pain can occur with many degenerative disorders and is less characteristic for initial presentation than early axial back symptoms.
The client has been diagnosed with secondary syphilis. Which is an appropriate assessment for the nurse to enter into the client’s record?
- Chancre ulcers
- No significant symptoms
- Nodular, pustular, annular lesions
- Destructive lesions involving many organs and tissues
Explanation: Answer reason: Papulosquamous eruptions that can be annular, sometimes pustular, and widespread are consistent with this stage. A chancre is the hallmark of primary infection, while a period with few/no symptoms is more typical of latent syphilis. Destructive, multi-organ lesions are characteristic of tertiary disease (gummas and late complications), not secondary infection.
Client education about gout includes which information?
- Good foot care will reduce complications.
- Increased dietary intake of purine is needed.
- Production of uric acid in the kidney affects joints.
- Uric acid crystals cause inflammatory destruction of the joint.
Explanation: Answer reason: Gout is driven by hyperuricemia with precipitation of monosodium urate crystals in joints, which triggers an intense inflammatory response and can lead to joint damage over time. Patient education should include this core disease mechanism to support adherence to urate-lowering therapy and flare prevention strategies. Increased purine intake is incorrect because high-purine foods raise uric acid and can precipitate attacks. The statement about uric acid production in the kidney is inaccurate because uric acid is primarily produced from purine metabolism (mainly in the liver) and the kidney primarily excretes it.
A 70-year-old male client is diagnosed with syphilis in the secondary stage. Which finding should the nurse expect during assessment?
- Chronic bone and joint irritation
- Tender lymphadenopathy
- Generalized rash on the palms and soles
- Personality changes and mental confusion
Explanation: Answer reason: A diffuse maculopapular rash that commonly involves the palms and soles is a hallmark feature and is highly testable. Lymphadenopathy can occur but is typically generalized and often non-tender, making that option less characteristic. Bone/joint involvement and neuropsychiatric changes are more consistent with late (tertiary) disease manifestations such as gummatous lesions or neurosyphilis.
A 6-year-old boy is admitted to a pediatric unit for treatment of osteomyelitis. The nurse knows that osteomyelitis is most commonly caused by which organism?
- Staphylococcus epidermidis
- Escherichia coli O157.H7
- Pneumocystis carinii
- Staphylococcus aureus
Explanation: Answer reason: This organism has virulence factors (e.g., adhesins, toxins) that promote tissue invasion and persistence, making it the classic cause of acute osteomyelitis in pediatrics. A frequent distractor is coagulase-negative staphylococci, which are more associated with prosthetic material or indwelling devices rather than typical community-acquired pediatric bone infection. The other options are not typical causes of osteomyelitis in an immunocompetent child and are more linked to gastrointestinal or opportunistic pulmonary infections.
A 69-year-old client develops acute shortness of breath and progressive hypoxia requiring mechanical ventilation after repair of a fractured right femur. The nurse determines that the hypoxia was probably a result of which condition?
- Asthma attack
- Atelectasis
- Bronchitis
- Fat embolism
Explanation: Answer reason: This leads to sudden dyspnea with rapidly worsening hypoxemia that can progress to respiratory failure requiring mechanical ventilation. The timing after femur fracture/repair strongly points to this mechanism. Atelectasis is common post-op but typically causes milder hypoxemia and improves with coughing, deep breathing, and mobilization rather than rapidly progressing to severe ventilatory failure. Asthma attack and bronchitis are less directly linked to the precipitating event and do not fit the classic post–long-bone fracture complication.
A 3-year-old child has palpable purpura of the buttocks and lower extremities. Which condition would the nurse suspect with these symptoms?
- Child abuse
- Henoch-Schönlein purpura (HSP)
- Idiopathic thrombocytopenic purpura (ITP)
- Rocky Mountain spotted fever
Explanation: Answer reason: This condition causes inflammation of dermal vessels, creating raised (palpable), nonblanching purpura rather than flat petechiae/bruising. ITP more typically presents with petechiae and mucosal bleeding due to thrombocytopenia, not a vasculitic palpable rash in this distribution. Rocky Mountain spotted fever often begins on wrists/ankles with systemic toxicity and later spreads, making it less consistent with the described pattern.
A child comes to the emergency department feeling feverish and lethargic. Which assessment finding suggests Reye’s syndrome to the nurse?
- Fever, profoundly impaired consciousness, and hepatomegaly
- Fever, splenomegaly, and hyperactive reflexes
- Afebrile, intractable vomiting, and rhinorrhea
- Malaise, cough, and sore throat
Explanation: Answer reason: The hallmark clinical picture is encephalopathy (rapidly worsening level of consciousness) together with liver involvement such as hepatomegaly and hepatic dysfunction. The other options describe nonspecific viral upper respiratory symptoms or findings (e.g., splenomegaly) that do not capture the characteristic combination of acute altered mental status plus hepatic enlargement. This pattern should prompt urgent evaluation for increased intracranial pressure and liver failure risk.
All of the following are true of chronic fatigue syndrome EXCEPT?
- It may have a genetic component.
- It is also known as myalgic encephalomyelitis.
- It is a psychological disorder.
- It often begins with flu-like symptoms that do not go away.
- It may be triggered by a viral infection.
Explanation: Answer reason: Chronic fatigue syndrome (also termed myalgic encephalomyelitis/CFS) is understood as a complex, multisystem medical condition rather than a primary psychiatric illness. It commonly follows an infectious-like prodrome with persistent fatigue and other systemic symptoms, which aligns with post-viral onset patterns described in many patients. Familial clustering and research into heritability support the possibility of genetic susceptibility. Psychological symptoms can be comorbid or secondary to chronic illness, but they do not define the disorder’s etiology, making this statement the exception.
Which of the following statements about Reye syndrome is FALSE?
- It is associated with aspirin use.
- It is a complication that may occur in chickenpox infection.
- It mostly affects older adults.
- Symptoms may include vomiting, drowsiness, or behavior changes.
- Prolonged neurological problems may occur.
Explanation: Answer reason: Reye syndrome is an acute encephalopathy with hepatic dysfunction classically seen in children, especially after viral illnesses when salicylates are used. The statement is false because the typical population is pediatric rather than older adults, and the association with influenza or varicella infections is well described. Nausea/vomiting followed by altered mental status (e.g., drowsiness, behavior changes) reflects rising intracranial pressure and cerebral edema, fitting the clinical picture. Neurologic sequelae can persist in survivors if significant brain injury occurs, so that option remains plausible.
The new nurse asks the experienced nurse on the oncology unit why there are more adolescents than clients of other age groups with osteosarcoma. The experienced nurse explains that osteosarcoma has a peak incidence during adolescence due to which occurrence?
- Increase in hormonal production
- Closure of epiphyseal growth plates
- Rapid growth spurt at this time
- Increase in sports-related injuries
Explanation: Answer reason: During adolescence, accelerated skeletal growth increases cellular proliferation and bone remodeling, which raises the chance of malignant transformation in bone-forming cells. This explains the peak incidence in teenagers and why common sites are around the knee and proximal humerus. Closure of growth plates occurs toward the end of adolescence and would not account for the earlier peak. Sports injuries may prompt evaluation but are not a causative driver of tumor development.
Pulmonary embolism and deep venous thrombosis (DVT) are two manifestations of the same disease. The risk factors for pulmonary embolism are the risk factors for thrombus formation within the venous circulation. These risk factors are known as Virchow’s triad and include?
- Decreased central venous pressures.
- Hypocoagulability.
- Injury to the bone.
- Venous stasis.
Explanation: Answer reason: Virchow’s triad describes the three major mechanisms that promote venous thrombosis: stasis of blood flow, endothelial injury, and hypercoagulability. Sluggish venous return (e.g., immobility, heart failure, prolonged travel) allows clotting factors to accumulate and increases the likelihood of thrombus formation that can embolize to the lungs. One distractor is “hypocoagulability,” which would reduce clot formation rather than promote it; the triad includes hypercoagulability instead. The other options are not core elements of the triad as classically defined (it is endothelial injury, not bone injury, and stasis is not defined by decreased central venous pressure).
The adolescent, who has been sick for several days, is being seen in a clinic with a tentative diagnosis of mononucleosis. Which findings should the nurse expect when assessing the client?
- Weakness, loss of appetite, and extreme constipation
- Fever, an enlarged spleen, and a rash similar to chicken pox
- White coating on the throat and depressed lymphocyte levels
- Extreme fatigue and enlarged lymph nodes in the neck and axilla
Explanation: Answer reason: The illness often includes pharyngitis and fever, but prominent, persistent fatigue with tender/enlarged nodes is a hallmark assessment finding. A varicella-like rash is not a typical expected finding (a rash is more associated with giving amoxicillin/ampicillin during EBV infection), making that choice less fitting. Depressed lymphocyte levels are inconsistent because mono commonly causes lymphocytosis with atypical lymphocytes rather than lymphopenia.
The client asks the nurse to look at a lesion on the client’s body. Which characteristics should prompt the nurse to consider that the client may have a basal cell carcinoma (BCC)?
- Nodular in appearance, depression in the center, and has a “pearly” characteristic
- Irregular color, surface, and border, less than one centimeter, and appears eroded
- Dry, hyperkeratotic scaly-like papule and has the appearance similar to a wart
- Vesiculopustular lesion with a thick, honey- colored crust and pruritic in nature
Explanation: Answer reason: This description matches the typical morphology that should trigger suspicion and prompt dermatologic evaluation/biopsy. In contrast, irregular color and border cues are more characteristic of melanoma warning signs, not the classic BCC appearance. A dry hyperkeratotic wart-like papule is more consistent with actinic keratosis or squamous cell carcinoma spectrum, while honey-colored crusted pruritic lesions suggest impetigo.
The nurse is aware that which assessment finding distinguishes bulimia nervosa from binge-eating disorder?
- Binge-eating disorder is not associated with the regular use of inappropriate compensatory behaviors (such as purging, fasting, and excessive exercise).
- Binge eating occurs at least two times a week in bulimia nervosa but not in binge-eating disorder.
- Bulimia nervosa clients eat food within a 2-hour time frame in amounts that surpass any amount most people would eat in a similar period of time.
- A sense of lack of control over eating during the episode is found in a client with a binge-eating disorder.
Explanation: Answer reason: The key distinguishing feature between these two eating disorders is the presence of recurrent inappropriate compensatory behaviors. Bulimia nervosa includes behaviors such as self-induced vomiting, misuse of laxatives/diuretics, fasting, or excessive exercise to prevent weight gain after binges, whereas binge-eating disorder does not. Both conditions can involve binge episodes characterized by eating an unusually large amount of food in a discrete period and feeling a lack of control during the episode, so those findings do not differentiate them. Frequency-based statements here are unreliable as a discriminator because binge frequency criteria have varied and are not the defining difference.
The nurse is providing care for a client admitted to the burn unit. Select the most appropriate statement that identifies the nutritional needs of the client?
- The client needs 100 cal/kg throughout hospitalization.
- The hypermetabolic state after a burn injury contributes to poor healing.
- A cool environment decreases caloric demand.
- Maintaining a hypermetabolic rate decreases the client’s risk of infection.
Explanation: Answer reason: Severe burns trigger a catecholamine- and cytokine-driven hypermetabolic, hypercatabolic response that markedly increases energy and protein requirements. If these needs are not met, the patient develops negative nitrogen balance, loss of lean body mass, impaired collagen synthesis, and delayed wound closure. This physiologic state therefore directly contributes to poor healing unless aggressive nutritional support is provided. A common distractor is the “cool environment” idea; warmer ambient temperature actually helps reduce heat loss and metabolic demand in major burns, not cool temperatures.
When reviewing the client’s medical record, the experienced nurse discovers that the client’s breast cancer is staged as T4 N3 M1. Which comment made by the experienced nurse to the new nurse is correct?
- “This client has a 3-cm breast tumor that has spread to only one lymph node.”
- “The TNM system is used to classify solid tumors by size and degree of spread.”
- “The higher the number in the TNM system, the better the chances are for a cure.”
- “This TNM system helps to classify tumors as either well- or poorly differentiated.”
Explanation: Answer reason: TNM staging describes the primary tumor extent (T), regional lymph node involvement (N), and presence of distant metastasis (M), which together reflect disease burden and spread. T4 and N3 indicate advanced local tumor extension and extensive nodal disease, and M1 indicates distant metastasis. Option A is incorrect because it describes limited tumor size and minimal nodal spread, which contradicts T4 N3 and does not address M1. Higher TNM categories generally correlate with worse prognosis (making C incorrect), and tumor differentiation is graded separately (e.g., histologic grade), not classified by TNM (making D incorrect).
The nurse should assess the client with bladder cancer for which of the following?
- Suprapubic pain.
- Painless hematuria
- Dysuria
- Urine retention
Explanation: Answer reason: This finding is a key red-flag symptom that should prompt evaluation even when there is no pain or urinary burning. Dysuria and suprapubic pain more commonly suggest cystitis or other inflammatory lower urinary tract conditions rather than an early bladder tumor. Urinary retention can occur with outlet obstruction (e.g., prostate enlargement) or advanced disease but is not the typical hallmark presentation compared with painless hematuria.
Premature closure of coronal suture is known as?
- Albert Syndrome
- Apert Syndrome
- Neurofibromatosis
- Trachoma
Explanation: Answer reason: Apert syndrome classically involves coronal craniosynostosis (often bilateral) along with midface hypoplasia and syndactyly. The other choices do not describe craniosynostosis: neurofibromatosis is a neurocutaneous tumor syndrome, and trachoma is an infectious eye disease. Therefore, the syndrome name most directly linked to premature coronal suture closure is the correct selection.
Most common cause of death due to burns in early period is?
- Sepsis
- Hypovolemic shock
- Both
- None
Explanation: Answer reason: This burn shock is most prominent in the first 24–48 hours and is the leading early killer without rapid, adequate fluid resuscitation. Infection-related mortality typically rises later after several days as wound colonization and immune dysfunction progress. Therefore the earliest period is dominated by circulatory collapse rather than infection.
The healthcare provider is caring for a patient with a diagnosis of polyarteritis nodosa. Which of the following clinical signs are consistent with this diagnosis?
- Chest pain
- Hematochezia
- Peripheral neuropathy
- Hypertension
- Hemoptysis
Explanation: Answer reason: This mechanism produces elevated blood pressure and is a classic, high-yield clinical feature. Peripheral neuropathy and GI ischemic symptoms can occur, but the prompt asks for the single best sign most characteristic and broadly testable. Hemoptysis is more typical of small-vessel vasculitides with pulmonary capillaritis rather than this condition.
An adolescent client has a pending diagnosis of Hodgkin's lymphoma. Which test result does the nurse correlate with this type of cancer?
- Reed-Sternberg cells present
- Lymphocytic WBCs present
- Philadelphia chromosome present
- Reactive lymph nodes present
Explanation: Answer reason: This finding is highly specific and is the classic diagnostic correlation for Hodgkin lymphoma compared with other hematologic malignancies. In contrast, the Philadelphia chromosome is classically associated with chronic myelogenous leukemia and some cases of ALL, not Hodgkin lymphoma. “Reactive lymph nodes” and nonspecific lymphocytosis can occur with infections or inflammatory conditions and do not establish this diagnosis.
The nurse is caring for a client with systemic lupus erythematosus (SLE). The major complication associated with systemic lupus erythematosus is?
- Nephritis
- Cardiomegaly
- Desquamation
- Meningitis
Explanation: Answer reason: Lupus nephritis can progress to significant proteinuria, hematuria, hypertension, and ultimately chronic kidney disease or renal failure, making it a major complication and key driver of morbidity and mortality. Cardiac involvement can occur (e.g., pericarditis), but cardiomegaly is not the classic major complication emphasized for SLE. Desquamation is not a defining systemic complication of SLE, and meningitis is an uncommon neurologic manifestation compared with renal involvement.
A slight bluish discoloration around the navel is a sign of hemoperitoneum?
- Kernig's sign
- Cullen's sign
- Kehr's sign
- Brudzinski's sign
Explanation: Answer reason: This finding is specifically named Cullen’s sign and points to significant internal bleeding rather than superficial bruising. By contrast, Kernig’s and Brudzinski’s signs indicate meningeal irritation in meningitis, not abdominal bleeding. Kehr’s sign is referred shoulder pain from diaphragmatic irritation (often splenic injury), which is a different clinical clue than periumbilical discoloration.
A client is reviewing the results of recent lab work and diagnostic tests. In addition to an elevated white blood cell count, the nurse assesses worsening pain in the right lower quadrant. The nurse suspects appendicitis and would correctly state which factor to be the most likely cause?
- Obstruction by stone fecal matter
- Inflammation with excessive loose stool
- Embolism of the mesenteric arteries
- Inflammation of the large bowel
Explanation: Answer reason: Appendicitis most commonly begins with obstruction of the appendiceal lumen, which leads to mucus accumulation, rising intraluminal pressure, venous congestion, bacterial overgrowth, and subsequent inflammation with leukocytosis and localized right lower quadrant pain. A fecalith (hardened fecal material) is a classic obstructing source and directly explains the progressive pain pattern described. Excessive loose stools are not a typical primary cause of appendiceal obstruction and are more consistent with infectious gastroenteritis. Mesenteric arterial embolism causes acute intestinal ischemia with severe, diffuse pain out of proportion to exam rather than a focal RLQ process, while large-bowel inflammation points more toward colitis/diverticulitis than appendicitis.
Early appendicitis pain usually starts at...?
- Right iliac fossa
- Supraorbital region
- Epigastrium
- Periumbilical region
Explanation: Answer reason: As the inflammation progresses to involve the parietal peritoneum, pain localizes to the right lower quadrant/right iliac fossa at McBurney’s point. This migration pattern helps distinguish early visceral pain from later somatic, localized peritoneal pain. Options like epigastrium or supraorbital region do not match midgut visceral referral patterns typical of appendicitis.
Forschheimer’s sign?
- Seen in rubella
- Are red macules or petechiae confined to the hard palate.
- Found after 2nd day of the rash
- Pathognomonic of rubeola
Explanation: Answer reason: Forchheimer sign refers to enanthem consisting of small red macules/petechiae on the soft palate and is classically associated with rubella. It is not confined to the hard palate, making that description inaccurate. It is also not pathognomonic for rubeola, which is instead characterized by Koplik spots.
Which of the following is a risk factor for hypovolemic shock?
- Hemorrhage
- Antigen-antibody reaction
- Gram-negative bacteria
- Vasodilation
Explanation: Answer reason: Acute blood loss directly decreases circulating volume and oxygen-carrying capacity, making it a classic and primary precipitant. In contrast, an antigen-antibody reaction and gram-negative bacteria are typical triggers for distributive shock (anaphylactic and septic) where vasodilation and capillary leak predominate. Vasodilation itself describes the mechanism of distributive shock rather than a volume-loss risk factor.
Which type of cancer has the poorest prognosis?
- Squamous cell carcinoma
- Breast Cancer
- Pancreatic cancer
- Gastric cancer
Explanation: Answer reason: Pancreatic cancer is typically asymptomatic until advanced, has aggressive biology with early local invasion and distant spread, and only a small minority are surgical candidates at presentation. As a result, overall 5-year survival remains among the lowest of major solid tumors. By contrast, many breast cancers have effective screening and systemic therapies, and squamous cell carcinomas (depending on site) are often detected earlier and can be locally treated.
Which of the following signs and symptoms would Nurse include in teaching plan as an early manifestation of laryngeal cancer?
- Stomatitis
- Airway obstruction
- Hoarseness
- Dysphagia
Explanation: Answer reason: This makes hoarseness appear sooner than obstructive symptoms, which generally occur later when the tumor enlarges and narrows the airway. Dysphagia is more typical of involvement of adjacent pharyngeal/esophageal structures or more advanced local disease. Stomatitis is an inflammatory mouth condition and is not a characteristic early manifestation of laryngeal malignancy.
It is leading cause of death in Infants and Young children-?
- Pneumonia
- Congenital anomalies
- Diarrheal infection
- Communicable diseases
Explanation: Answer reason: g., complex congenital heart disease, neural tube defects) early in life, sometimes before effective treatment is possible. This cause category remains prominent even as many infectious causes decline with immunization, sanitation, and antibiotic access. In contrast, pneumonia and diarrheal disease are important under-5 killers globally, but as single specific diagnoses they are not typically cited as the overall leading cause across infants and young children in standard pediatric mortality summaries. The broad term “communicable diseases” is nonspecific and overlaps multiple etiologies, making it a weaker best-answer choice than a defined leading category.
Which is not a cause of jaundice in the newborn?
- Decrease bilirubin conjugation
- Impaired bilirubin excretion
- Bilirubin hyperexcretion
- Bilirubin overproduction
Explanation: Answer reason: Newborns commonly have reduced UDP-glucuronyl transferase activity, so decreased conjugation raises unconjugated bilirubin. Increased bilirubin production from high RBC turnover or hemolysis and impaired excretion due to cholestasis or obstruction can also elevate bilirubin levels. In contrast, increased excretion would lower bilirubin rather than cause jaundice, making it the option that does not fit the pathophysiology.
The abnormal development of tissue epithelium is?
- Mataplasia
- Dysplasia
- Anaplasia
- Hyperplasia
Explanation: Answer reason: It commonly arises in epithelial tissues under chronic irritation or oncogenic influences and is considered a premalignant change in many settings (e.g., cervical intraepithelial neoplasia). Metaplasia is a reversible substitution of one mature cell type for another, not “abnormal development.” Hyperplasia is an increase in the number of cells with preserved differentiation. Anaplasia describes loss of differentiation typical of malignant tumors rather than the precursor abnormal epithelial development described here.
During a routine physical examination, a firm mass is palpated in the right breast of a 35-year-old woman. Which of the following findings or client history would suggest cancer of the breast as opposed to fibrocystic disease?
- History of early menarche
- Cyclic changes in mass size
- History of anovulatory cycles
- Increased vascularity of the breast
Explanation: Answer reason: That historical factor therefore supports malignancy risk rather than benign fibrocystic change. In contrast, cyclic changes in size are classic for fibrocystic disease because symptoms fluctuate with the menstrual cycle. Anovulatory cycles are more associated with benign hormonal irregularity and do not specifically point toward carcinoma, and “increased vascularity” is not a typical discriminating clinical feature compared with the hormone-related patterning of fibrocystic changes.
A child is admitted to the hospital with a diagnosis of Wilms tumor, stage II. Which of the following statements most accurately describes this stage?
- The tumor is less than 3 cm. in size and requires no chemotherapy
- The tumor did not extend beyond the kidney and was completely resected
- The tumor extended beyond the kidney but was completely resected
- The tumor has spread into the abdominal cavity and cannot be resected
Explanation: Answer reason: Stage II indicates the tumor extends beyond the kidney (e.g., into perirenal tissues or vessels) but remains completely resectable with no gross residual disease. Stage I is confined to the kidney and completely resected, matching a common distractor. More extensive peritoneal spread or unresectable disease would correspond to higher stages rather than stage II.
Brodie’s abscess is a form of?
- Chronic osteonecrosis
- Chronic exostosis
- Chronic osteomyelitis
- Bone Tumor
Explanation: Answer reason: The defining concept is chronic osteomyelitis with a contained nidus of infection and surrounding sclerotic bone. Osteonecrosis is ischemic bone death rather than infection, and exostosis is benign bony outgrowth without suppuration. Although it can mimic a bone tumor radiographically, its pathology and clinical context are infectious, not neoplastic.
Which statement about appendicitis is accurate and true?
- A high fiber diet is risk factor associated with appendicitis
- Appendicitis is more common among females than males
- Mc burney's point tenderness is suggestive of appendicitis
- Left lower quadrant pain is suggestive of appendicitis
Explanation: Answer reason: Maximal tenderness at McBurney’s point (about one-third of the distance from the anterior superior iliac spine to the umbilicus) is a well-known exam finding that supports this diagnosis. A high-fiber diet is generally protective because it reduces constipation and fecalith formation, so it is not a typical risk factor. Pain is usually periumbilical early and then migrates to the right lower quadrant rather than presenting as left lower quadrant pain.
What stage of illness is characterized by general signs and symptoms, such as malaise?
- Convalescence
- Illness
- Incubation
- Prodromal
Explanation: Answer reason: g., malaise, fatigue, low-grade discomfort) begin to appear before the full clinical picture develops. This contrasts with the incubation period, when the pathogen is present but the person is asymptomatic. The illness stage is when the characteristic, specific signs and symptoms are most evident and peak in severity. Convalescence is the recovery phase, with symptoms resolving and strength returning.
A community health nurse visits the Gapuz family because the brothers Gian, 4, and Lean, 5, were diagnosed several years ago as having Duchenne muscular dystrophy. The nurse teaches Mr. and Mrs. Gapuz about muscular dystrophy, including therapeutic management and nursing considerations. Which of the following statements would most likely indicate that Mr. Gapuz has understood the teaching?
- "The boys will probably be unable to walk independently by the time they are 9 to 11 years of age."
- "I understand that muscle relaxants can be ineffective in some children."
- "When the boys are a little older, they can have surgery to improve their ability to walk."
- "We will help the boys be as active as possible so as to prevent progression of the disease."
Explanation: Answer reason: " Duchenne muscular dystrophy is a progressive X-linked myopathy with predictable loss of ambulation in late childhood due to ongoing muscle fiber degeneration and weakness. A key teaching point for families is anticipating functional decline and planning early for mobility supports, contracture prevention, and respiratory/cardiac monitoring as the disease advances. Muscle relaxants are not a core therapeutic strategy for altering the disease course, and their effectiveness is not a central management concept in DMD education. Surgery may be used selectively for contractures or scoliosis but does not reliably restore or improve independent walking. Activity should be balanced and low-impact to maintain function and prevent complications, but it cannot prevent progression of the underlying genetic disease.
Which of the following conditions is not a complication of Hodgkin’s disease?
- Anemia
- Infection
- Myocardial Infarction
- Nausea
Explanation: Answer reason: This leads to cytopenias such as anemia and increased susceptibility to infection. Nausea is also commonly encountered as a complication related to systemic illness and, more prominently, to treatments like chemotherapy and radiation. Myocardial infarction is not a typical direct complication of Hodgkin’s disease itself, making it the best choice as the exception.
Swelling of body called?
- Edema
- Anemia
- Fever
- Vomit
Explanation: Answer reason: The medical term for this tissue fluid accumulation is edema. Anemia is decreased oxygen-carrying capacity due to low hemoglobin or red cell mass, not swelling. Fever is elevated body temperature from altered hypothalamic set point, and vomiting is forceful expulsion of gastric contents—neither describes tissue swelling.
Think you’re ready for the NCLEX?
Run through a full 150-question exam just like the real thing. You’ll hit the 85-question checkpoint and get a clear report showing where you stand.
