Diagnostic Tests Practice Test 5
Diagnostic Tests NCLEX Practice Test
Diagnostic Tests is a key topic within the NCLEX test plan, located under Physiological Integrity → Reduction of Risk Potential → Diagnostic Tests. This section prepares patients, explains procedures, and interprets findings for safe follow-up care. Each test contains 50 questions designed to mirror the difficulty and variety of the real exam.
This is the 5th part of the Diagnostic Tests series. To explore all practice tests under this topic, use the “Back to Main Topic” button at the end of the page.
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In the Diagnostic Tests Study Cards section, shared by real NCLEX candidates, you’ll find concise summaries and high-yield insights related to the most tested concepts. It’s a perfect space to reinforce challenging topics and sharpen your recall through quick, focused repetitions. Short, powerful, and repeatable!
Diagnostic Tests Practice Test 5
What is the best initial action for the nurse when a patient presents with a chest pain.?
- Give nitroglycerin
- Assess for pain level
- Perform an ECG
- Administer aspirin
Explanation: Answer reason: A 12-lead ECG should be obtained immediately to rapidly identify life-threatening ischemia or STEMI and guide time-sensitive interventions. Diagnostic confirmation drives safe sequencing of therapies (e.g., nitrates can be contraindicated in right ventricular infarct or recent PDE-5 inhibitor use). While pain assessment and antiplatelet therapy are important, they should not delay immediate cardiac evaluation when chest pain suggests acute coronary syndrome. Early ECG also establishes a baseline for ongoing comparison if symptoms evolve. Category reason: This is a patient-care prioritization question focused on the nurse’s first action and urgent evaluation of chest pain, emphasizing timely diagnostic testing to reduce risk.
Which diagnostic test is commonly done before thoracentesis?
- ECG
- CT scan
- Chest X-ray
- Colonoscopy
Explanation: Answer reason: It is used to confirm the presence and approximate location/size of a pleural effusion and to help guide planning for the procedure to reduce complication risk (e.g., pneumothorax, organ puncture). Bedside ultrasound is often preferred for real-time guidance, but among the listed choices this is the standard pre-procedure test. ECG does not localize pleural fluid, CT is not routinely required for most uncomplicated effusions, and colonoscopy is unrelated. Category reason: This tests selection of an appropriate pre-procedure diagnostic study to reduce risk and guide a thoracentesis, aligning with NCLEX content on diagnostic tests and preventing complications.
A client is scheduled for a Holter monitor test. Which instruction should the nurse include?
- Avoid all physical activity during the test
- Record all your physical activities and symptoms during the test
- Do not eat or drink while wearing the monitor
- Stay in bed during the monitoring period
Explanation: Answer reason: A Holter monitor correlates the heart rhythm tracing with the client’s activities and any symptoms such as palpitations, dizziness, or chest discomfort. Keeping a detailed activity/symptom diary allows the provider to match events to ECG changes and improves diagnostic accuracy. Clients are typically encouraged to continue usual daily activities (unless otherwise instructed) to capture rhythms during real-life exertion rather than restricting movement. Eating and drinking are generally allowed; the key is keeping electrodes/monitor dry and intact. Category reason: This is a nursing education question about preparing a client for a cardiac diagnostic test and ensuring accurate data collection, which fits Diagnostic Tests under Reduction of Risk Potential.
Scenario: A nurse needs to collect a sputum specimen for culture. What instruction will the nurse give the patient?
- Brush your teeth before collecting the sample.
- Spit into the container after coughing deeply.
- Drink fluids first to help.
- Rinse your mouth and then breathe normally.
Explanation: Answer reason: A sputum culture requires specimen from the lower respiratory tract, so the patient should take deep breaths and cough forcefully to bring up sputum, rather than saliva. Collecting saliva can contaminate the specimen and reduce the accuracy of the culture results. Typical best practice is to collect in a sterile container, ideally first thing in the morning after oral rinsing (without antiseptic mouthwash) and before eating or drinking. Category reason: This question tests a nursing instruction for collecting a diagnostic specimen to ensure accurate laboratory testing, which fits Diagnostic Tests under Reduction of Risk Potential.
Lilia is scheduled to have a hysterosalpingogram. Which of the following instructions would you give her regarding this procedure?
- She will not be able to conceive for 3 months after the procedure
- The sonogram of the uterus will reveal any tumors present
- Many women experience mild bleeding as an after effect
- She may feel some cramping when the dye is inserted
Explanation: Answer reason: D. She may feel some cramping when the dye is inserted An HSG involves instilling contrast through the cervix to outline the uterine cavity and fallopian tubes under fluoroscopy; uterine distention commonly causes transient cramping similar to menstrual cramps. Teaching about expected sensations helps reduce anxiety and promotes cooperation during the test. It does not require avoiding conception for months, and the procedure is not a sonogram. While light spotting can occur, the key pre-procedure expectation to emphasize is cramping with contrast injection. Category reason: This item asks what patient teaching/instruction to provide for a diagnostic procedure (hysterosalpingogram), which fits nursing care around Diagnostic Tests under Reduction of Risk Potential.
Hyperbilirubinemia in Newborns A nurse is caring for a newborn with jaundice at 24 hours. What is the priority action?
- Start phototherapy
- Encourage frequent breastfeeding
- Check the total bilirubin level
- Administer IV fluids
Explanation: Answer reason: Jaundice appearing within the first 24 hours is pathologic until proven otherwise and requires prompt evaluation. Measuring a total serum bilirubin (or validated transcutaneous bilirubin with confirmatory serum if indicated) determines severity, risk of kernicterus, and guides treatment thresholds for phototherapy or exchange transfusion. Phototherapy is initiated based on age-in-hours nomograms and risk factors rather than appearance alone. Breastfeeding support is important but does not replace immediate diagnostic assessment in early-onset jaundice. Category reason: This question asks for the nurse’s priority action and emphasizes obtaining a diagnostic value to guide safe treatment decisions, which aligns with Diagnostic Tests under Reduction of Risk Potential.
A 24 year-old female client is scheduled for surgery in the morning. Which of the following is the primary responsibility of the nurse?
- Taking the vital signs
- Obtaining the permit
- Explaining the procedure
- Checking the lab work
Explanation: Answer reason: Preoperative nursing responsibility prioritizes identifying and reducing perioperative risk through verification of required diagnostics and readiness for anesthesia/surgery. Reviewing laboratory results helps detect issues such as anemia, electrolyte abnormalities, pregnancy status, or coagulation problems that could require postponement or specific interventions to prevent complications. Vital signs are important but are a routine task and do not by themselves confirm surgical readiness or uncover critical contraindications. Obtaining the surgical consent and explaining the procedure are primarily the provider’s responsibilities, while the nurse’s role is to verify the consent is present and clarify questions within scope.
A client is preparing to undergo a cystoscopy for stones. Which of the following statements indicates that the client understands the procedure?
- I better drink a lot of fluid now because I won't be able to after the test.
- I will probably see a little blood when I urinate.
- I will be able to go home after 3 days in the hospital.
- I won't need any pain medicine; this probably will not hurt.
Explanation: Answer reason: Cystoscopy commonly causes transient dysuria and mild hematuria due to urethral/bladder mucosal irritation from instrumentation. Recognizing a small amount of blood in the urine as an expected short-term finding reflects accurate understanding of normal post-procedure effects. In contrast, patients are typically encouraged to increase oral fluids after the test (not restrict them), and cystoscopy is often outpatient rather than requiring multiple inpatient days. Discomfort is also common, so assuming no need for pain relief is unrealistic and suggests misunderstanding.
Which of the following methods would the nurse use to collect a urine sample for culture and sensitivity testing in a 16-month-old client?
- Apply a urine collection bag to the perineum
- Aspirate a specimen from an indwelling catheter collection bag
- Insert a sterile intermittent urinary catheter
- Place cotton balls inside the diaper
Explanation: Answer reason: A perineal urine collection bag has a high contamination rate from skin flora and commonly yields false-positive cultures. Sampling from an indwelling catheter collection bag is unreliable because urine can sit and become contaminated, and specimen should be taken from the catheter sampling port using sterile technique. Cotton balls in a diaper are not sterile and can introduce fibers/skin organisms, making the sample unsuitable for culture.
Position given to patient during sigmoidoscopy??
- Supine
- Prone
- Lithotomy
- Left Lateral
Explanation: Answer reason: This positioning uses gravity and natural anatomic curvature to help advance the scope and reduce looping. It also allows better access to the anus and supports patient stability and privacy during the procedure. Supine and prone positions make insertion and maneuvering more difficult, while lithotomy is more commonly used for gynecologic exams and is not the standard for sigmoidoscopy.
A client is admitted for an MRI. The nurse should question the client regarding?
- Pregnancy
- A titanium hip replacement
- Allergies to antibiotics
- Inability to move his feet
Explanation: Answer reason: MRI screening focuses on identifying conditions that could increase risk from the magnetic field and, when used, gadolinium-based contrast. Pregnancy is a key pre-procedure screening question because elective imaging decisions and contrast use are handled more cautiously due to potential fetal risk and limited safety data, especially early in gestation. A titanium hip replacement is typically MRI-compatible and is not the primary “question/contraindication” concern compared with ferromagnetic implants or devices. Antibiotic allergies are not directly relevant to MRI unless a medication/contrast reaction history is being assessed, and inability to move the feet is a clinical symptom rather than an MRI safety screening issue.
A female client admitted to the hospital with a neurological problem asks the nurse whether magnetic resonance imaging may be done. The nurse interprets that the client may be ineligible for this diagnostic procedure based on the client's history of?
- Hypertension
- Heart failure
- Prosthetic valve replacement
- Chronic obstructive pulmonary disorder
Explanation: Answer reason: A history of valve replacement raises concern for an older or non–MRI-conditional prosthetic valve, which may be a contraindication or require careful verification of device type before scanning. The nurse’s key safety role is to screen for implanted metal and ensure the MRI team has exact device information (manufacturer, model, MRI compatibility) prior to proceeding. In contrast, conditions like hypertension or heart failure are not inherent MRI contraindications, and COPD mainly affects positioning/ability to lie flat rather than magnetic safety.
Sigmoidoscopy done in which position?
- Lithotomy
- Jack knife
- Fowler's
- Knee chest
Explanation: Answer reason: The knee-chest position achieves this by flexing the hips and elevating the pelvis, helping the sigmoidoscope pass more easily and improving visualization. It also helps reduce looping and discomfort compared with positions that do not align the distal colon as well. Lithotomy is more typical for gynecologic/perineal procedures, while Fowler’s is primarily for respiratory comfort and does not facilitate lower GI scope insertion.
A nurse is preparing to obtain a sputum specimen from a male client. Which of the following nursing actions will facilitate obtaining the specimen?
- Limiting fluid
- Having the client take deep breaths
- Asking the client to spit into the collection container
- Asking the client to obtain the specimen after eating
Explanation: Answer reason: A high-quality sputum specimen should come from the tracheobronchial tree, so measures that enhance lung expansion and loosen mucus improve yield. In contrast, simply spitting into a container often results in an oral saliva sample that is not diagnostically useful. Limiting fluids can thicken secretions and make expectoration harder, and obtaining the specimen after eating increases contamination risk and may trigger nausea or emesis.
A patient is having a colonoscopy procedure performed. How should the patient be instructed to prepare for the procedure?
- NPO for 8-12 hours before the procedure.
- D/C all HTN Rx for two days prior to the procedure.
- Take three Dulcolax tablets and two containers of Miralax the day before to clear out the lower GI system.
- None of the above prep is necessary for this type of procedure.
Explanation: Answer reason: Colonoscopy requires a clear colon so the mucosa can be visualized and lesions are not missed. A bowel-prep regimen using a stimulant laxative plus an osmotic agent the day before is an appropriate instruction to achieve adequate cleansing. Being NPO alone does not clean the colon; it mainly reduces aspiration risk around sedation and is incomplete preparation by itself. Stopping antihypertensives for two days is unsafe and not standard; medication adjustments are individualized (e.g., some agents may be held the morning of the procedure). Therefore, the bowel-cleansing preparation is the best answer among the options provided.
You are planning to draw an arterial blood gas from your patient, but you must perform an Allen’s test first. You know that the Allen’s test is used to test what?
- Popliteal circulation
- Ulnar circulation
- Femoral circulation
- Carotid circulation
Explanation: Answer reason: Allen’s test assesses patency of the ulnar artery (via the palmar arch) to ensure the hand will remain perfused if the radial artery spasms or becomes occluded after an ABG. A normal test shows rapid return of hand color after releasing ulnar compression, indicating sufficient collateral flow. This prevents ischemic complications and is why it is performed prior to radial arterial sampling rather than evaluating leg or carotid circulation.
Which of the following should the nurse implement to prepare a client for a KUB (Kidney, Ureter, Bladder) radiograph test?
- Client must be NPO before the examination
- Enema to be administered prior to the examination
- Medicate client with Lasix 20 mg IV 30 minutes prior to the examination
- No special orders are necessary for this examination
Explanation: Answer reason: The nursing priority is to remove radiopaque objects (e.g., jewelry, metal snaps) and verify pregnancy status when applicable, rather than implement restrictive prep orders. An enema is more associated with certain GI studies (e.g., barium enema) when bowel clearance is essential for visualization. Diuretics like furosemide are used for specific urinary tract imaging protocols, not for a standard KUB.
A client is scheduled to have a blood test for cholesterol and triglycerides the next day. The nurse would tell the client?
- Be sure and eat a fat-free diet until the test.
- Do not eat or drink anything but water for 12 hours before the blood test.
- Have the blood drawn within 2 hours of eating breakfast.
- Stay at the laboratory so 2 blood samples can be drawn an hour apart.
Explanation: Answer reason: Accurate lipid measurement requires a fasting specimen because recent dietary fat and carbohydrate intake can transiently raise serum triglycerides and affect calculated lipid values. Fasting for about 9–12 hours with water only minimizes postprandial lipemia and improves reliability and comparability of results. Advising a fat-free diet without fasting does not prevent post-meal triglyceride elevations. Drawing the blood shortly after breakfast would increase the chance of falsely elevated triglycerides and an uninterpretable panel.
A client is scheduled for an Intravenous Pyelogram (IVP). In order to prepare the client for this test, the nurse would?
- Instruct the client to maintain a regular diet the day prior to the examination
- Restrict the client's fluid intake 4 hours prior to the examination
- Administer a laxative to the client the evening before the examination
- Inform the client that only 1 x-ray of his abdomen is necessary
Explanation: Answer reason: Bowel prep (often a laxative the evening before, sometimes with dietary restrictions per protocol) helps reduce stool in the colon and improves diagnostic accuracy. Routine regular diet the day before is not typical because many protocols use light diet/NPO instructions to optimize imaging and safety. Telling the client only one abdominal x-ray is needed is incorrect because IVP involves a series of timed films to track contrast through the urinary system.
Which of these observations made by the nurse during an excretory urogram indicate a complication?
- The client complains of a salty taste in the mouth when the dye is injected
- The client's entire body turns a bright red color
- The client states "I have a feeling of getting warm."
- The client gags and complains " I am getting sick."
Explanation: Answer reason: Generalized flushing/erythema involving the whole body suggests a systemic reaction to iodinated contrast and is not an expected, benign sensation. In contrast, a transient warm feeling and a metallic/salty taste are common, self-limited effects of IV contrast and usually require only reassurance and monitoring. Nausea/gagging can occur with anxiety or contrast effects, but diffuse bright redness is more concerning for a significant reaction and warrants immediate assessment and emergency readiness.
The nurse is preparing a client who will undergo a myelogram. Which of the following statements by the client indicates a contraindication for this test?
- "I can't lie in 1 position for more than thirty minutes."
- "I am allergic to shrimp."
- "I suffer from claustrophobia."
- "I developed a severe headache after a spinal tap."
Explanation: Answer reason: " Myelography uses iodinated contrast introduced into the subarachnoid space, so a significant concern is prior hypersensitivity to iodinated contrast media. A history framed as “shellfish (shrimp) allergy” is commonly tested as a proxy for iodine/contrast allergy risk and should prompt further assessment and potential premedication or alternative imaging rather than proceeding routinely. The other statements describe issues that can be managed as positioning/sedation considerations or expected prior post–lumbar puncture effects, not a direct contraindication to the diagnostic test itself. The safest nursing judgment is to treat a reported contrast-related allergy risk as a red-flag requiring provider notification before the study.
A nurse is to collect a sputum specimen for acid-fast bacillus (AFB) from a client. Which action should the nurse take first?
- Ask client to cough sputum into container
- Have the client take several deep breaths
- Provide a appropriate specimen container
- Assist with oral hygiene
Explanation: Answer reason: Having the sterile, properly labeled container ready at the bedside is the key preparation step before coaching the client to breathe deeply and cough. If the client coughs before the container is available, sputum may be swallowed, spit into an inappropriate receptacle, or contaminate surfaces, requiring recollection. Oral hygiene can be helpful for reducing oral contaminants, but it is not the initial priority over ensuring correct equipment is immediately available for collection.
Which of these tests with frequency would the nurse expect to monitor for the evaluation of clients with poor glycemic control in persons aged 18 and older?
- A glycosylated hemoglobin (A1c) should be performed during an initial assessment and during follow-up assessments, which should occur at no longer than 3-month intervals
- A glycosylated hemoglobin is to be obtained at least twice a year
- A fasting glucose and a glycosylated hemoglobin is to be obtained at 3 months intervals after the initial assessment
- A glucose tolerance test, a fasting glucose and a glycosylated hemoglobin should be obtained at 6-month intervals after the initial assessment
Explanation: Answer reason: In adults with poor glycemic control or after treatment adjustments, monitoring at intervals up to every 3 months best matches the biologic window of erythrocyte glycation and allows timely intensification of management. Testing only twice yearly is appropriate for stable, well-controlled clients, not those with poor control. Routine glucose tolerance testing is not used for ongoing monitoring, and adding fasting glucose at fixed intervals is less useful than serial A1c for overall control assessment.
A client with colon cancer is having a barium enema. The nurse should instruct the client to take which type of medication after the procedure is completed?
- Laxative
- Anticholinergic
- Antacid
- Demulcent
Explanation: Answer reason: A medication that promotes stool passage helps expel retained barium and reduces post-procedure complications. Increased fluids and ambulation are also commonly encouraged, but among the listed medication types, this choice most directly addresses the expected risk. Anticholinergics can further slow GI motility and would worsen constipation rather than prevent it.
Sputum sample for AFB should be collected?
- Morning after wake up
- After breakfast
- In the evening
- Whenever the person cough
Explanation: Answer reason: Collecting before eating or drinking helps avoid contamination with food particles and reduces the chance the patient produces saliva instead of true deep-cough sputum. Timing “after breakfast” can dilute or contaminate the specimen and may reduce cough effectiveness. “Whenever the person cough” is nonspecific and increases the risk of inadequate samples, whereas early-morning collection targets the best-quality specimen for TB evaluation.
The client with suspected active pulmonary tuberculosis (TB) has a positive tuberculin skin test (TST). Which prescription from the health care provider does the nurse anticipate will confirm the diagnosis in this client?
- Collect 2 blood cultures from different intravenous sites after cleansing with a chlorhexidine swab
- Collect 2 early morning nose specimens (swabs) from each nare using sterile culturettes
- Collect an early morning sterile sputum specimen on 3 consecutive days
- Collect blood for the QuantiFERON-TB test after cleansing the site with a chlorhexidine swab
Explanation: Answer reason: Early-morning sputum is highest yield because secretions pool overnight, and obtaining specimens on multiple consecutive days increases diagnostic sensitivity. A positive TST and an IGRA (QuantiFERON) support infection/exposure but cannot distinguish latent from active disease and therefore do not confirm active pulmonary TB. Blood cultures and nasal swabs are not the standard confirmatory diagnostic approach for suspected pulmonary TB.
You are caring for a 95 year-old female resident with a history of Alzheimer's disease, anemia, and pyelonephritis. The family reports that she seems extremely confused, agitated, and restless. You prepare to call the provider with this information. Which of the following diagnostic tests?
- Serum lactate and CT of head
- Chest x-ray and renal ultrasound
- Blood cultures and 24-hr urine collection
- Urinalysis with cultures, CBC
Explanation: Answer reason: A urinalysis with culture directly assesses for bacteriuria/pyuria and identifies the pathogen to guide targeted antibiotics. A CBC helps detect leukocytosis or other hematologic clues of infection/sepsis severity and provides baseline data given her anemia history. A 24-hour urine collection is not useful for acute infectious workup and can delay diagnosis and treatment in a potentially time-sensitive condition.
The nurse is aware that a voiding cystourethrogram is performed by which of the following techniques?
- X-ray of the bladder and urethra after a Foley catheter has been placed.
- Ultrasound of the bladder and urethra after a Foley catheter has been placed.
- Ultrasound of the bladder and urethra while the patient is urinating.
- X-ray of the bladder and urethra while the patient is urinating.
Explanation: Answer reason: A voiding cystourethrogram (VCUG) is a fluoroscopic radiographic study used to evaluate the bladder and urethra dynamically during micturition, commonly to assess vesicoureteral reflux and urethral abnormalities. The technique requires contrast instilled into the bladder (typically via catheter) and imaging obtained as the patient voids, because reflux and urethral pathology may only be evident during the voiding phase. Ultrasound does not provide the same contrast-based, real-time visualization of reflux through the ureters. Imaging only after catheter placement without capturing voiding would miss the key “voiding” component of the study.
The nurse is aware that the patients who are allergic to intravenous contrast media are usually also allergic to which of the following products?
- Eggs
- Shellfish
- Soy
- Acidic fruits
Explanation: Answer reason: In many nursing exam contexts, shellfish allergy is treated as a proxy for “iodine allergy,” and therefore linked to higher perceived risk with iodinated IV contrast. This makes the shellfish choice the expected test answer when asked what patients “usually” are also allergic to. The other options are common food allergens but are not classically paired with IV contrast reactions in standard nursing test heuristics.
A client with a history of dysrhythmias is to wear a Holter monitor for 24 hours on an outpatient basis. What should the nurse teach the client to do while wearing the monitor?
- Discontinue medications.
- Avoid using a microwave oven.
- Keep a written account of activities.
- Record the blood pressure periodically.
Explanation: Answer reason: Holter monitoring correlates ECG rhythm changes with symptoms and what the client was doing at the time. A detailed activity and symptom diary (e.g., exertion, chest pain, palpitations, dizziness, medication times) allows the provider to match recorded dysrhythmias to triggers and clinical events. Stopping prescribed medications can worsen or unmask arrhythmias and is unsafe unless specifically ordered. Microwaves generally do not interfere with Holter monitors, and routine blood pressure logging is not the key data needed for interpreting ambulatory ECG recordings.
Which client statement indicates an understanding of the nurse's instructions concerning a Holter monitor?
- "The only times the monitor should be taken off is for showering and sleep."
- "The monitor will record my activities and symptoms if an abnormal rhythm occurs."
- "The results from the monitor will be used to determine the size and shape of my heart."
- The monitor will record any abnormal heart rhythms while I go about my usual activities."
Explanation: Answer reason: " A Holter monitor is an ambulatory ECG device used to continuously capture cardiac rhythm during normal daily life to correlate symptoms (e.g., palpitations, dizziness) with rhythm changes. Keeping usual activities helps provoke intermittent dysrhythmias that might not appear during a brief in-clinic ECG. The device is generally worn continuously and is not primarily intended to measure cardiac size/shape (that would be echocardiography or imaging). A common teaching point is also to keep a symptom/activity diary, but the monitor itself does not “record” activities—this makes the statement in option B inaccurate.
The nurse determines that a Mantoux tuberculin skin test is positive. To most accurately diagnose tuberculosis (TB), the nurse plans to consult with the physician to follow up the skin test with a?
- Chest x-ray
- Sputum culture
- Complete blood cell count
- Computed tomography scan of the chest
Explanation: Answer reason: Definitive diagnosis of active pulmonary TB requires identification of the organism, and culture (often alongside smear/NAAT) provides the highest diagnostic accuracy and enables drug-susceptibility testing. Imaging such as a chest x-ray can support suspicion and assess disease extent but cannot confirm TB because findings are not specific. CBC and chest CT may show nonspecific inflammatory changes or detail anatomy but do not establish the microbiologic diagnosis.
A client who had several episodes of chest pain is scheduled for an exercise electrocardiogram. Which explanation should the nurse include when teaching the client about this procedure?
- "This is a noninvasive test to check your heart's response to physical activity."
- "This test is the definitive method to identify the actual cause of your chest pain."
- "The findings of this test will be of minimal assistance in the treatment of angina."
- "The findings from this minimally invasive test will show how your body reacts to exercise."
Explanation: Answer reason: " An exercise electrocardiogram (treadmill stress test) evaluates cardiac electrical activity and symptoms during progressively increased physical exertion to detect exercise-induced ischemia. It is considered noninvasive because it uses external electrodes and exercise without entering the body. It is not a definitive test for the cause of chest pain; further testing (e.g., imaging stress tests or coronary angiography) may be required depending on risk and results. Calling it “minimally invasive” is inaccurate and can mislead clients about what will happen and what information the test provides.
The nurse assesses a client with acute left leg swelling and calf tenderness following a long car ride. The nurse anticipates that the primary healthcare provider (PHCP) will order which diagnostic test?
- D-dimer test
- Ankle-Brachial Index
- Radiograph (X-Ray)
- Venous Duplex Ultrasonography
Explanation: Answer reason: Compression duplex ultrasound is the first-line, noninvasive test that directly visualizes impaired venous compressibility/flow consistent with clot. D-dimer can support ruling out DVT in low-risk patients, but it is nonspecific and can be elevated for many reasons, so it is not the best confirmatory study here. Ankle-brachial index evaluates peripheral arterial disease, and plain X-ray does not diagnose venous thrombosis.
Which medication should a nurse withhold from a client 6 hours before a series of pulmonary function tests (PFTs)?
- Azithromycin
- Robitussin
- Albuterol
- Cefaclor
Explanation: Answer reason: Short-acting beta-agonists are commonly held for several hours prior to testing per lab protocol to assess true pre-bronchodilator function. Antibiotics do not directly change immediate airway caliber or lung volumes in a way that would confound same-day PFT measurements. Holding the bronchodilator helps ensure the test reflects the client’s untreated pulmonary status unless the test specifically includes post-bronchodilator measurements.
Which test should a nurse expect to be ordered for a client with severe abdominal pain in the midepigastric region, back tenderness, nausea, and vomiting?
- Amylase
- C-peptide
- Stool culture
- Colonoscopy
Explanation: Answer reason: Serum amylase (and often lipase) rises with pancreatic inflammation, so it is an expected initial diagnostic test. C-peptide is used to evaluate endogenous insulin production (e.g., diabetes workup), not acute epigastric pain. Stool culture and colonoscopy target infectious diarrhea or lower-GI pathology and do not fit the primary presentation.
A client has passed a renal calculus. The nurse sends the specimen to the laboratory so it can be analyzed for?
- Antibodies.
- Type of infection.
- Composition of calculus.
- Size and number of calculi.
Explanation: Answer reason: Stone analysis is used to identify the chemical makeup (e.g., calcium oxalate/phosphate, uric acid, struvite, cystine) so targeted prevention can be planned. Knowing the composition guides specific interventions such as thiazides for recurrent calcium stones, urine alkalinization for uric acid stones, or infection evaluation and eradication for struvite stones. Antibodies are not measured from a stone specimen, and infection type is determined by urine culture rather than stone chemistry. Stone size and number are assessed with imaging (e.g., CT/ultrasound), not by sending a passed fragment to the lab.
Which test should the nurse expect to be ordered for a client suspected of having diverticulosis?
- Abdominal ultrasound
- Barium enema
- Barium swallow
- Gastroscopy
Explanation: Answer reason: A contrast enema can demonstrate diverticular outpouchings along the colon wall and has been classically used to evaluate suspected diverticular disease. An abdominal ultrasound does not reliably visualize colonic diverticula, and a barium swallow evaluates the esophagus/stomach/upper GI tract rather than the colon. Gastroscopy also assesses the upper GI tract and would not be the appropriate test for suspected colonic diverticulosis.
For a definitive diagnosis of cirrhosis, the nurse will assist with which diagnostic test?
- Albumin level
- Bromsulphthalein dye excretion
- Liver biopsy
- Liver enzyme levels
Explanation: Answer reason: A tissue sample provides the highest specificity compared with indirect blood markers of synthetic function or hepatocellular injury. Albumin and liver enzyme levels can support suspicion and gauge severity but are neither sensitive nor specific enough to confirm cirrhosis. Older functional tests like bromsulphthalein clearance are not the standard confirmatory method and do not establish histologic diagnosis.
Which of the following is a noninvasive method of evaluating cardiac status in a child?
- Transthoracic echocardiogram
- Cardiac enzyme levels
- Cardiac catheterization
- Transesophageal pacing
Explanation: Answer reason: A transthoracic echocardiogram uses external ultrasound to visualize chambers, valves, and ventricular function, making it a standard noninvasive pediatric assessment. Cardiac catheterization is invasive because it requires intravascular access and instrumentation of the heart. Transesophageal pacing involves placing a device into the esophagus to deliver electrical impulses and is not an evaluation test but a therapeutic/diagnostic intervention with instrumentation, so it is not considered noninvasive.
The nurse teaches parents that which test is used to diagnose respiratory syncytial virus (RSV)?
- Blood test
- Nasopharyngeal washings
- Sputum culture
- Throat culture
Explanation: Answer reason: Nasopharyngeal washings (or swab/aspirate) provide an appropriate specimen for rapid antigen testing or PCR, which are commonly used to confirm RSV. Blood testing is not a standard diagnostic method for RSV because viremia is not the typical presentation. Throat culture and sputum culture are less reliable/less commonly used in infants and young children and are not the preferred specimen sites for confirming RSV.
Two days after undergoing a left thoracotomy, a client’s temperature is 38.9°C. The nurse notifies the physician, who orders two sets of blood cultures. Which amount of blood would the nurse obtain for cultures?
- 2 ml
- 5 ml
- 10 ml
Explanation: Answer reason: Standard adult practice is to draw about 10 mL per culture bottle (commonly 20 mL per set split into aerobic and anaerobic bottles), which maximizes sensitivity and reduces false-negative results. Smaller volumes significantly decrease the chance of recovering the causative organism and can delay appropriate therapy. In a febrile post-thoracotomy patient, correctly collected cultures before antibiotics are key to identifying a bloodstream infection source.
A client is scheduled for several tests. Which test should be performed after the thyroid function tests?
- Ultrasound of the carotid arteries
- EEG
- Chest X-ray
- Computed tomography scan of the head with contrast
Explanation: Answer reason: A head CT with contrast is the only option that involves iodinated contrast and therefore has the greatest potential to confound subsequent thyroid function or uptake evaluations. Non-contrast studies like ultrasound and EEG do not introduce iodine and do not meaningfully affect thyroid testing. Sequencing thyroid tests first helps prevent false or misleading results and avoids unnecessary repeat testing.
The nurse is caring for the client with a suspected DVT. For which diagnostic test should the nurse anticipate the client will need to be prepared?
- V/Q Scan
- Arteriogram
- Venogram
- Embolectomy
Explanation: Answer reason: This test requires nursing preparation focused on contrast administration considerations (e.g., allergy history, renal function, hydration, IV access) and post-procedure monitoring. A V/Q scan evaluates ventilation–perfusion mismatch and is used for suspected pulmonary embolism rather than locating a leg vein thrombus. An arteriogram assesses arterial flow, and an embolectomy is a therapeutic procedure, not a diagnostic test.
A client is scheduled for testing to diagnose an abdominal aortic aneurysm. The most definitive test would be?
- Abdominal X-ray
- Aortogram
- Computed tomography (CT) scan
- Ultrasound
Explanation: Answer reason: An aortogram (angiography) provides high-detail vascular imaging that can delineate the aneurysm’s extent and relationship to renal/iliac arteries, which is critical when intervention is considered. Ultrasound is an excellent noninvasive screening tool and can estimate size, but it is less definitive for detailed anatomy compared with angiographic imaging. A plain abdominal X-ray is nonspecific and may only show calcification, and CT is highly useful but is generally considered less “definitive” than direct angiographic visualization in classic NCLEX framing.
A nurse is preparing to teach a client with a hiatal hernia. The nurse should provide instruction on which diagnostic test?
- Colonoscopy
- Lower GI series
- Barium swallow
- Abdominal X-ray series
Explanation: Answer reason: A contrast esophagram can demonstrate herniation of the stomach through the diaphragm and associated reflux patterns, making it a direct test for this condition. Colonoscopy and a lower GI series assess the large bowel and would not evaluate the esophagogastric anatomy relevant to a hiatal hernia. A plain abdominal X-ray is generally not sensitive or specific for diagnosing this problem compared with contrast swallow studies.
A client is seen in the outpatient surgical clinic for a suspected diagnosis of gastric cancer. The nurse anticipates the diagnostic testing of the client will include which test?
- Barium enema
- Colonoscopy
- Endoscopy
- Serum chemistry levels
Explanation: Answer reason: Upper GI endoscopy (EGD) provides this direct assessment and tissue sampling, making it the key diagnostic test when gastric malignancy is suspected. Barium enema and colonoscopy evaluate the large intestine and do not assess the stomach, so they do not match the suspected site. Serum chemistry tests may reveal nonspecific abnormalities but cannot diagnose or localize gastric cancer.
A client is suspected of having cholecystitis. The nurse will prepare the client for which of the following diagnostic tests?
- Abdominal computed tomography (CT) scan
- Abdominal ultrasound
- Barium swallow
- Endoscopy
Explanation: Answer reason: It is widely available, noninvasive, and can be performed at the bedside, making it ideal for initial evaluation. CT may help when ultrasound is equivocal or complications are suspected, but it is not typically the initial test. Barium swallow and endoscopy evaluate esophageal/gastric pathology rather than gallbladder inflammation.
A client received a purified protein derivative (PPD) test for tuberculosis (TB) on the right forearm. The site is reddened and raised about 3 mm. The nurse interprets this result as?
- Indeterminate.
- Needs to be redone.
- Negative.
- Positive.
Explanation: Answer reason: PPD (Mantoux) interpretation is based on the measured induration in millimeters, not the amount of redness. An induration of about 3 mm is below all standard positive thresholds (e.g., 5 mm, 10 mm, or 15 mm depending on risk factors), so it is interpreted as a negative result. Mild erythema can occur from local irritation and does not indicate TB infection without sufficient induration. The test does not need to be repeated solely because the reaction is small unless there is concern for timing/reading error or a need for two-step testing in specific screening situations.
A client has received a preliminary diagnosis of tuberculosis. In order to obtain a definitive diagnosis, the nurse anticipates that the physician will order which test?
- Chest X-ray
- Mantoux test
- Sputum culture
- Tuberculin test
Explanation: Answer reason: Culture (often alongside smear/NAAT) directly detects the organism and allows drug-susceptibility testing, which guides therapy and infection-control decisions. A chest X-ray can suggest TB patterns but is not specific and cannot confirm etiology. Mantoux/tuberculin skin tests indicate prior exposure/immune sensitization and cannot distinguish latent from active disease.
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