Intravenous Therapy Practice Test 1
Intravenous Therapy NCLEX Practice Test
Intravenous Therapy is a key topic within the NCLEX test plan, located under Physiological Integrity → Pharmacological and Parenteral Therapies → Intravenous Therapy. This section manages IV fluids, site assessment, and complication prevention to maintain vascular integrity. Each test contains 50 questions designed to mirror the difficulty and variety of the real exam.
This is the 1st part of the Intravenous Therapy series. To explore all practice tests under this topic, use the “Back to Main Topic” button at the end of the page.
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Intravenous Therapy Practice Test 1
RL is a—?
- Isotonic solution
- Hypertonic solution
- Hypotonic solution
- None of these.
Explanation: Answer reason: Ringer’s lactate (RL) has an osmolarity close to that of plasma and is classified clinically as an isotonic crystalloid used for fluid resuscitation.
Which IV needle gauge and color are typically used for trauma and rapid infusion?
- 14 Gauge - Orange
- 16 Gauge - Gray
- 18 Gauge - Green
- 20 Gauge - Pink
- 22 gauge - blue
Explanation: Answer reason: For trauma and rapid infusion, a large-bore catheter is required; 14G (orange) provides the highest flow rates for rapid fluid and blood resuscitation.
Which-gauge needle is typically used for rapid fluid administration?
- 14G
- 24G
- 18G
- 20G
Explanation: Answer reason: A lower gauge means a larger bore, enabling the highest flow rates for rapid resuscitation; a 14G catheter is typically used for rapid fluid administration. 18G and 20G catheters allow slower flow, and 24G is small-bore.
Which cannula size is used for infants?
- 24-gauge
- 22-gauge
- 20-gauge
- 18-gauge
Explanation: Answer reason: Infants have small, fragile veins; a small-bore IV catheter, such as a 24-gauge, is preferred to minimize trauma and facilitate cannulation.
Normal flush volume administered before and after medication in paediatric patients?
- 10–30 mL
- 5–20 mL
- 2 mL
- 1 mL
Explanation: Answer reason: Pediatric IV lines are flushed with small volumes to clear the catheter without excess fluid, commonly about 2 mL of normal saline before and after medications.
A client with a head injury develops the syndrome of inappropriate antidiuretic hormone (SIADH). Which physician's prescription would the nurse question?
- D5W at 200 mL/hr
- Demeclocycline (Declomycin) 150 mg q6h
- Daily weights
- Intake and output q4h
Explanation: Answer reason: In SIADH, there is excess water retention and hyponatremia. D5W becomes free water and is hypotonic, which would worsen hyponatremia and fluid overload and is especially dangerous after head injury. Demeclocycline, daily weights, and strict intake/output are appropriate for SIADH management.
In a burn patient, to provide adequate fluids within 24 hours, what intravenous fluid is appropriate?
- D5 water
- Lactated Ringer's solution
- 0.9% NaCl solution
- D5NSS
Explanation: Answer reason: Initial burn resuscitation uses an isotonic crystalloid, specifically Lactated Ringer's, which best matches plasma and helps buffer acidosis. Dextrose solutions are not resuscitative, and NS can cause hyperchloremic acidosis with large volumes.
The RN on the oncology unit is preparing to mix and administer amphotericin B (Fungizone) to a client. Which action is contraindicated when administering this drug IV?
- Mix the drug with normal saline solution.
- Administer the drug over 4–6 hours.
- Hydrate with IV fluids two hours before the infusion.
- Premedicate the client with the ordered acetaminophen (Tylenol) and diphenhydramine (Benadryl).
Explanation: Answer reason: Conventional amphotericin B must be diluted in D5W only; it is incompatible with normal saline. Slow infusion, prehydration, and premedication are recommended to reduce adverse reactions.
What is the IV fluid of choice for a patient with severe dehydration?
- 5% dextrose
- DNS
- Ringer's lactate
- IV albumin
Explanation: Answer reason: For rapid volume replacement in severe dehydration/hypovolemia, an isotonic crystalloid is indicated; Ringer lactate is preferred. D5W becomes hypotonic and does not expand intravascular volume, DNS is hypertonic and not first-line for resuscitation, and albumin is not indicated for routine dehydration.
A client is undergoing fluid replacement after being burned over 20% of her body 12 hours ago. The nursing assessment reveals a blood pressure of 90/50 mm Hg, a pulse rate of 110 beats per minute, and a urine output of 20 mL in the past hour. The nurse reports the findings to the health care provider (HCP) and anticipates which prescription?
- Transfusing one unit of packed red blood cells
- Administering a diuretic to increase urine output.
- Increasing the amount of intravenous (IV) lactated Ringer's solution administered per hour.
- Changing the IV lactated Ringer’s solution to one containing 5% dextrose in water
Explanation: Answer reason: Findings indicate hypovolemia during the early burn resuscitation phase (hypotension, tachycardia, low urine output). The appropriate action is to increase isotonic crystalloid (lactated Ringer’s) infusion. Diuretics and D5W are contraindicated; PRBCs are not indicated without hemorrhage.
A client is brought to the emergency department unresponsive, and a diagnosis of hyperosmolar hyperglycemic syndrome is made. Which anticipated health care provider's prescription would the nurse immediately prepare to initiate?
- Endotracheal intubation
- 100 units of NPH insulin.
- Intravenous infusion of normal saline.
- Intravenous infusion of sodium bicarbonate
Explanation: Answer reason: HHS presents with profound dehydration; the immediate priority is aggressive fluid resuscitation with isotonic saline before insulin therapy. NPH insulin is inappropriate, bicarbonate is not indicated, and intubation is only needed if airway compromise is evident.
A client is admitted to a hospital with a diagnosis of diabetic ketoacidosis (DKA). The initial blood glucose level is 950 mg/dL (54.2 mmol/L). A continuous intravenous (IV) infusion of short-acting insulin has been initiated, along with IV rehydration with normal saline. The serum glucose level has now decreased to 240 mg/dL (13.7 mmol/L). Which medication would the nurse prepare to administer next?
- An ampule of 50% dextrose.
- NPH insulin, subcutaneously.
- IV fluids containing dextrose
- Phenytoin for the prevention of seizures
Explanation: Answer reason: In DKA, once glucose falls to about 200–250 mg/dL, dextrose is added to IV fluids to prevent hypoglycemia while continuing insulin to clear ketosis.
NaCl 0.9% is also called?
- Hypotonic
- Hypertonic
- Acidic
- Isotonic
Explanation: Answer reason: 0.9% sodium chloride (normal saline) has an osmolarity similar to plasma and is classified as an isotonic solution.
DNS fluid contains?
- Only water
- Only glucose
- Only NaCl
- Glucose + NS
Explanation: Answer reason: DNS stands for Dextrose Normal Saline; it contains glucose (dextrose) with 0.9% sodium chloride.
What is NaCl 0.9% (Normal Saline) used for?
- Increase sodium rapidly
- Treat low sugar
- Provide hydration
- Treat allergy
Explanation: Answer reason: 0.9% NaCl is an isotonic crystalloid used for volume expansion and maintenance of hydration; it does not rapidly correct sodium, treat hypoglycemia, or manage allergies.
Commonest site for IV cannulation in adults?
- Cephalic vein
- Femoral vein
- Jugular vein
- Radial vein
Explanation: Answer reason: The cephalic vein in the forearm/hand is the most commonly used peripheral site for IV cannulation in adults. Femoral and jugular veins are central access sites, and the radial vein is not typically preferred for routine peripheral IVs.
Irritation, swelling, warmth and redness at the intravenous infusion site is the sign of?
- Venous thrombosis
- Thrombophlebitis
- Bacteremia
- Embolism
Explanation: Answer reason: Localized irritation, swelling, warmth, and erythema at an IV site are classic signs of vein inflammation with clot—thrombophlebitis. Venous thrombosis, bacteremia, and embolism present with broader systemic signs.
A client receiving chemotherapy reports severe nausea and vomiting despite taking prescribed antiemetics; which intervention should the nurse prioritize?
- Administer intravenous fluids as prescribed
- Encourage the client to eat small, frequent meals
- Increase the dose of the current antiemetic
- Teach the client relaxation techniques to manage symptoms
Explanation: Answer reason: Severe vomiting puts the client at immediate risk for dehydration and electrolyte imbalance. The priority is to restore and maintain fluid status by administering IV fluids as prescribed. Increasing the antiemetic dose requires a provider order, and dietary or relaxation measures are lower priority in acute dehydration risk.
A client with sickle cell disease is admitted in active labor. Which nursing intervention would be most helpful in preventing a sickling crisis?
- Obtaining blood pressures every 2 hours
- Administering pain medication every 3–4 hours as ordered
- Monitoring arterial blood gas results
- Administering IV fluids at ordered rate of 200 mL/hr
Explanation: Answer reason: Aggressive hydration decreases blood viscosity and helps prevent sickling during labor. The other options do not directly prevent a crisis.
A client arrives in the emergency room with severe burns of the hands, right arm, face, and neck. The nurse needs to start an IV. Which site would be most suitable for this client?
- Top of client’s right hand
- Left antecubital fossa
- Top of either foot
- Left forearm
Explanation: Answer reason: Use an unburned extremity and avoid areas of flexion and adult feet. The left forearm provides intact, stable veins; the right hand is burned, the AC fossa is a flexion site, and feet are last-resort in adults.
Which type of intravenous fluid should the nurse anticipate administering first to a client admitted with severe dehydration?
- Hypertonic solution (e.g., 3% saline)
- Hypotonic solution (e.g., 0.45% saline)
- Isotonic solution (e.g., 0.9% saline)
- Colloid solution (e.g., albumin)
Explanation: Answer reason: Initial management of severe dehydration is rapid intravascular volume expansion with an isotonic crystalloid (e.g., 0.9% NS or LR). Hypotonic fluids worsen hypotension, hypertonic saline is reserved for specific indications like severe hyponatremia, and colloids are not first-line for routine volume resuscitation.
For a 76-year-old woman, where should the home health nurse start an IV with 5% dextrose in water (D5W)?
- The veins of the client’s wrist on the nondominant side.
- The veins of the leg so it will not interfere with the client’s ability to feed herself.
- The dorsal veins of the client’s forearm on the nondominant side.
- The dorsal surface of the client’s hand on the nondominant side.
Explanation: Answer reason: For older adults, choose a stable, well-supported peripheral vein on the nondominant side and avoid areas of flexion and lower extremities. Forearm dorsal veins provide good flow and reduce complications; leg veins and wrist/hand sites have higher risks of thrombosis, infiltration, and interference with function.
Which action should the nurse take before performing venipuncture to initiate continuous intravenous (IV) therapy?
- Apply a cool compress to the affected area
- Inspect the IV solution and expiration date
- Secure a padded arm board above the IV site
- Apply a tourniquet below the venipuncture site
Explanation: Answer reason: Before initiating IV therapy, the nurse must verify the solution and its expiration date to ensure safety and correct therapy. A tourniquet is applied above, not below, the site; cool compress is inappropriate (warmth promotes venous dilation); and an arm board is used after insertion if needed for stabilization.
What is the appropriate nursing action when infiltration is observed at the vascular access site during continuous infusion of isotonic fluids?
- Reduce the infusion rate and elevate the affected extremity.
- Stop the infusion and remove the intravenous (IV) catheter.
- Stop the infusion and reposition the intravenous (IV) catheter into the vein.
- Reduce the infusion rate and apply warm compress to the intravenous (IV) site.
Explanation: Answer reason: Infiltration indicates the IV is no longer in the vein; the priority is to stop the infusion and remove the catheter to prevent further tissue injury. Then elevate and apply compresses per policy.
A client is receiving intravenous (IV) vancomycin. What action should the nurse take to prevent complications?
- Administer the medication rapidly to ensure effectiveness
- Monitor the IV site for redness and swelling
- Encourage the client to ambulate frequently
- Increase fluid intake to flush out the medication
Explanation: Answer reason: Vancomycin can cause phlebitis and infusion reactions; monitoring the IV site for redness and swelling helps prevent/identify complications. Rapid infusion increases risk (red man syndrome), and the other options are not indicated.
First choice of IV puncture site is?
- Veins in the scalp
- Veins of the forearm
- Veins in the foot
- Veins in the hand
Explanation: Answer reason: Forearm peripheral veins are preferred for IV cannulation: they are accessible, have good flow, and are less prone to kinking and complications compared with hand, foot, or scalp in adults.
In hypotension which fluid is provided?
- Normal saline
- Dextrose 10%
- NS 3%
- Ringer lactate
Explanation: Answer reason: Initial fluid for hypotension is an isotonic crystalloid to rapidly expand intravascular volume; 0.9% normal saline is the standard first-line choice. D10% and 3% saline are not used for volume resuscitation, and Ringer lactate is acceptable but NS is the typical initial fluid.
Which priority assessment should the nurse make before administering cisplatin to a client with cancer?
- Cancer staging
- Sodium level
- Intravenous (IV) patency
- Hemoglobin and hematocrit
Explanation: Answer reason: Cisplatin is a vesicant; extravasation can cause severe tissue injury. Ensuring the IV line is patent is the priority assessment immediately before infusion.
Which IV fluid is most appropriate for an obstetric client admitted with dehydration?
- Normal saline
- Dextrose in water
- Lactated Ringer's
- Dextrose 5% in 0.45 normal saline
- Dextrose 1% in water
Explanation: Answer reason: LR is an isotonic, balanced crystalloid commonly used in obstetrics for volume replacement in dehydration; it restores intravascular volume without unnecessary dextrose. Other dextrose solutions are not first-line for initial rehydration.
Which intravenous (IV) complication is characterized by pain, edema, erythema, formation of blisters, necrotic tissue, slough, or eschar due to leakage of a vesicant agent into surrounding tissues?
- Infection
- Phlebitis
- Infiltration
- Extravasation
- Hematoma
Explanation: Answer reason: Extravasation is the leakage of a vesicant into surrounding tissue, causing pain, erythema, edema, blistering, and potentially necrosis or eschar. Infiltration involves non-vesicant fluids and does not cause tissue necrosis.
Which of the following fluid solutions is hypertonic?
- 5% dextrose in 0.9% normal saline (NS)
- 5% dextrose in 0.45% normal saline (NS)
- 5% dextrose in Ringer's lactate (RL)
- All of the above
Explanation: Answer reason: D5NS, D5 0.45% NS, and D5 Ringer’s lactate all have osmolarity higher than plasma due to added dextrose, making them hypertonic; therefore all are correct.
The nurse is administering an intravenous vesicant chemotherapeutic agent to a client. Which assessment would require the nurse's IMMEDIATE action?
- Stomatitis lesion in the mouth
- Severe nausea and vomiting
- Complaints of pain at site of infusion
- A rash on the client's extremities
Explanation: Answer reason: Pain at the IV site during infusion of a vesicant suggests extravasation, which can cause tissue necrosis and requires immediate intervention. The other findings are common chemo side effects and are not as urgent.
While administering a chemotherapeutic vesicant, the nurse notes that there is a lack of blood return from the IV catheter. The nurse should?
- Stop the medication from infusing
- Flush the IV catheter with normal saline
- Apply a tourniquet and call the doctor
- Continue the IV and assess the site for edema
Explanation: Answer reason: Absence of blood return during vesicant chemotherapy suggests possible infiltration/extravasation. The priority is to stop the infusion immediately to prevent tissue injury; do not flush or continue.
The physician has ordered Dextrose 5% in normal saline for an infant admitted with gastroenteritis. The advantage of administering the infant's IV through a scalp vein is?
- The infant can be held and comforted more easily.
- Dextrose is best absorbed from the scalp veins.
- Scalp veins do not infiltrate like peripheral veins.
- There are few pain receptors in the infant's scalp.
Explanation: Answer reason: Scalp-vein IVs in infants keep the extremities free and are easier to secure, allowing the infant to be held and comforted without dislodging the line. The other statements are incorrect: drug absorption is the same IV, scalp veins can infiltrate, and the scalp is not lacking pain receptors.
The nurse is caring for an infant receiving intravenous fluid. Signs of fluid overload in an infant include?
- Swelling of the hands and increased temperature
- Increased heart rate and increased blood pressure
- Swelling of the feet and increased temperature
- Decreased heart rate and decreased blood pressure
Explanation: Answer reason: Fluid volume excess typically presents with hypertension and a bounding, often tachycardic pulse. Fever is not characteristic of fluid overload, and hypotension/bradycardia suggest volume deficit or shock.
Which colour cannula corresponds to 24 gauge?
- Pink
- Green
- Yellow
- Blue
Explanation: Answer reason: Standard IV cannula color coding: 24-gauge is yellow (22G blue, 20G pink, 18G green).
An obstetric client is admitted with dehydration. Which IV fluid would be most appropriate for the client?
- 45 normal saline
- Dextrose 1% in water
- Lactated Ringer's
- Dextrose 5% in .45 normal saline
Explanation: Answer reason: Dehydration requires isotonic fluid to restore intravascular volume. Lactated Ringer's is isotonic and commonly used in obstetrics; the other options are hypotonic or hypertonic and not first-line for volume replacement.
Which of the following is the most common site for venipuncture?
- Femoral vein
- Basilic vein
- Cephalic vein
- Median cubital vein
Explanation: Answer reason: The median cubital vein in the antecubital fossa is large, superficial, and well anchored with fewer nearby nerves, making it the preferred and most common site for venipuncture.
Which gauge size is appropriate for intravenous therapy?
- 18G
- 20G
- 22G
- 16G
Explanation: Answer reason: A 20-gauge catheter is the standard size for routine adult IV therapy, providing adequate flow for most fluids and medications with less trauma than large-bore catheters. 16G–18G are for rapid infusions/blood; 22G is used for small or fragile veins with slower flow.
What type of solution is 5% dextrose in normal saline (NS)?
- Isotonic solution
- Hypotonic solution
- Hypertonic solution
- None of the above
Explanation: Answer reason: D5NS has an osmolarity higher than plasma (~560 mOsm/L); therefore it acts as a hypertonic IV solution.
The client who is admitted with thrombophlebitis has an order for heparin. The medication should be administered using a/an?
- Buretrol
- Infusion controller
- Intravenous filter
- Three-way stop-cock
Explanation: Answer reason: Heparin is a high-alert medication requiring precise rate control to prevent overdose or bleeding; it should be infused with an IV infusion device/controller rather than a buretrol, filter, or stop-cock.
An elderly client is diagnosed with ovarian cancer. She has surgery followed by chemotherapy with a fluorouracil (Adrucil) IV. What should the nurse do if she notices crystals in the IV medication?
- Discard the solution and order a new bag
- Warm the solution
- Continue the infusion and document the finding
- Discontinue the medication
Explanation: Answer reason: Visible crystals indicate precipitation/instability of the IV drug; administering is unsafe. Do not attempt to redissolve or continue. Discard and obtain a new, clear solution.
What is the normal flush volume administered before and after medication in pediatric patients?
- 10-30 ml
- 5-20 ml
- 2 ml
- 1 ml
Explanation: Answer reason: Pediatric IV medication administration typically uses a normal saline flush of about 5–20 mL, adjusted to age, catheter size, and medication. Smaller volumes like 1–2 mL are inadequate; 10–30 mL is generally excessive for pediatrics.
Which type of solution is Ringer's Lactate (RL) an example of?
- Hypertonic solution
- Isotonic solution
- Hypotonic solution
Explanation: Answer reason: Lactated Ringer’s is a balanced crystalloid with osmolarity close to plasma, making it an isotonic IV solution used for volume replacement.
What is the correct angle for an intravenous (IV) injection?
- 0 degree
- 30 degree
- 45 degree
- 90 degree
Explanation: Answer reason: IV catheter is inserted with bevel up at a shallow angle of about 15–30 degrees to enter the vein; among the options, 30 degrees is correct.
What is the appropriate gauge size of the intravenous cannula used for neonates?
- 17G
- 18G
- 20G
- 22G
- 24G
Explanation: Answer reason: Neonates have very small, fragile veins; the smallest standard peripheral IV cannula is preferred. A 24G catheter is typically used in neonates to minimize vessel trauma and infiltration risk.
Promethazine hydrochloride (Phenergan) 25 mg IV push has been ordered for a patient. Before administering this medication to the patient, the nurse should check the?
- Color of the medication solution.
- Patient's pulse and temperature.
- Time of the last analgesic dose the patient received.
- Patency of the patient's vein.
Explanation: Answer reason: For an IV push medication—especially a vesicant like promethazine—the priority is to verify IV patency to prevent extravasation and tissue injury. The other options are not required checks immediately prior to this IV push.
A woman has returned from surgery after a right mastectomy with an IV of 0.9% NaCl infusing at 100 cc/hour into her left forearm. Several hours later, the IV infiltrates. The nurse is supervising a student nurse preparing to insert a new peripheral intravenous catheter. The nurse would intervene in which of the following situations?
- The student nurse selects a site where the veins are soft and elastic.
- The student nurse selects a site on the distal portion of the left arm.
- The student nurse selects a site close to the joint to provide for stability.
- The student nurse holds the skin taut to stabilize the vein.
Explanation: Answer reason: IV sites should avoid areas of flexion (near joints) to prevent dislodgement and infiltration. Choosing soft, elastic veins, starting distally, and stabilizing the vein by holding skin taut are correct techniques.
A fluid challenge of 250 cc of normal saline infused over 15 min is ordered for a client with possible acute renal failure. The nurse understands that the fluid challenge is given to?
- Rule out dehydration as the cause of oliguria.
- Increase cardiac output and fluid volume.
- Promote the transfer of intravascular fluid to the intracellular space.
- Dilute the level of waste products in the intravascular fluid.
Explanation: Answer reason: A normal-saline fluid challenge is used to determine if oliguria is due to prerenal hypovolemia/dehydration; improved urine output after the bolus supports dehydration. It is not intended to shift fluid intracellularly or simply dilute wastes, and increasing cardiac output is not the primary purpose.
Which IV cannula size is typically used for rapid fluid resuscitation in adults?
- 20G
- 18G
- 16G
- 14G
Explanation: Answer reason: Rapid fluid resuscitation in adult patients requires the fastest possible intravenous flow rate. Larger-bore IV cannulas allow greater fluid flow due to a wider internal diameter, following Poiseuille’s law. Among the available options (14G, 16G, 18G, 20G), 14G has the largest lumen and provides the highest flow rate, making it the preferred choice for rapid fluid resuscitation, trauma management, and massive volume replacement. Smaller gauges such as 18G or 20G do not allow sufficiently rapid infusion in emergency situations.
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